Urinary phthalate metabolite concentrations and blood glucose levels during pregnancy

International Journal of Hygiene and Environmental Health
Candace RobledoJean R Goodman

Abstract

To examine associations between phthalate metabolite urinary concentrations during early pregnancy and blood glucose levels obtained at the time of screening for gestational diabetes mellitus (GDM). Upon initiation of prenatal care, women with a mean gestational age of 12.8 weeks were recruited for a study of environmental chemical exposures (n = 110) and provided a spot urinary specimen. Blood glucose concentrations (mg/dl) were obtained from the electronic medical record for those patients who did not experience a pregnancy loss and did not transfer care to another facility prior to glucose screening (n = 72). Urinary concentrations of nine phthalate metabolites and creatinine were measured at the US Centers for Disease Control and Prevention. Associations between tertiles of phthalate metabolites concentrations and blood glucose levels were estimated using linear regression. Compared to pregnant women in the lowest concentration tertile, women with the highest urinary concentrations (≥ 3 rd tertile) of mono-iso-butyl phthalate (tertile: ≥ 15.3 μg/l, β = -18.3, 95% CI: -35.4, -1.2) and monobenzyl phthalate (tertile: ≥ 30.3 μg/l, β = -17.3, 95% CI: -34.1, -0.4) had lower blood glucose levels at the time of GDM screening after ...Continue Reading

References

Jan 1, 1973·Environmental Health Perspectives·P R Graham
May 11, 2002·Environmental Health Perspectives·Jane A HoppinDonna D Baird
Dec 5, 2003·Lancet·Edmond A Ryan
Oct 20, 2005·Occupational and Environmental Medicine·R Hauser, A M Calafat
Feb 10, 2006·International Journal of Andrology·Ted Schettler
Oct 5, 2006·Human & Experimental Toxicology·Marcela I MartinelliClaudio A Bernal
Jul 3, 2007·Molecular Nutrition & Food Research·Hanne FrederiksenAnna-Maria Andersson
Dec 12, 2007·International Journal of Andrology·Matthias Wittassek, Jürgen Angerer
Apr 17, 2008·Environmental Health Perspectives·Jennifer J AdibiRuss Hauser
Jan 24, 2009·Environmental Health Perspectives·Erin P HinesSuzanne E Fenton
Feb 19, 2009·Journal of Exposure Science & Environmental Epidemiology·Jennifer David PeckSusan L Schantz
May 13, 2009·Molecular and Cellular Endocrinology·Béatrice DesvergneCristina Casals-Casas
Aug 13, 2010·Chemosphere·Elizabeth Ann IrvinLuke P Naeher
Jun 24, 2011·Environmental Research·Katherine SvenssonLizbeth López-Carrillo
Jan 21, 2012·Environmental Health Perspectives·Joe M BraunRuss Hauser

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Citations

Jun 15, 2018·Environmental Health : a Global Access Science Source·Tamarra M James-ToddUNKNOWN EARTH Study Team
Sep 29, 2020·Frontiers in Public Health·Yiyu QianYing Hua
May 10, 2021·Environment International·Haotian WuAndrea L Deierlein

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