PMID: 46182Feb 1, 1975

Urinary polyamine levels in human cancer

A LiptonG F Kessler


Polyamine levels (putrescine, spermidine, spermine) were determined in 24-hour urine samples by a high voltage electrophoresis technique. Normal values were established in 42 normal volunteers. Thirty-eight of 56 patients with metastatic cancer had two or more levels elevated. Approximately two-thirds of patients with metastatic adenocarcinoma, metastatic squamous cell cancer or metastatic disease to the liver, lings, or bones had elevated levels. All 6 patients with localized malignant tumors had elevated urinary polyamine levels. Elevations were also seen in patients with benign prostatic hypertrophy and bronchial adenoma.


Jan 1, 1976·Journal of Surgical Oncology·M M Copeland
Jan 1, 1977·Journal of Surgical Oncology·K NishiokaM J McMurtrey
Jan 1, 1986·Journal of Neuro-oncology·Y TakaueJ van Eys
Jun 25, 1979·Archives of Dermatological Research·S Sakakibara, K Yoshikawa
Dec 1, 1986·Diseases of the Colon and Rectum·J S ThompsonK Laughlin
Apr 6, 1978·Biochimica Et Biophysica Acta·J JänneA Raina
Jun 1, 1987·Clinical Biochemistry·K IsobeS Otsuji
May 1, 2001·International Journal of Urology : Official Journal of the Japanese Urological Association·D SatoM Matsushima
Jan 1, 1980·Archives of Disease in Childhood·G B Barlow
May 1, 1983·Journal of Clinical Pathology·R Carachi, J G Beeley
Dec 1, 1979·The Journal of Clinical Investigation·D RudmanR Bain
Mar 1, 1980·Journal of Clinical Chemistry and Clinical Biochemistry. Zeitschrift Für Klinische Chemie Und Klinische Biochemie·G MilanoC M Lalanne
Dec 1, 1978·Journal of Pharmaceutical Sciences·M M Abdel-Monem, K Ohno
Oct 1, 1978·British Journal of Diseases of the Chest·R C CoombesA M Neville
Jul 1, 1986·European Journal of Cancer & Clinical Oncology·D M OtaD Dixon
Jul 1, 1982·European Journal of Cancer & Clinical Oncology·A ThyssC M Lalanne
Jan 1, 1984·Cell Biochemistry and Function·R Chayen
Jan 1, 1983·Critical Reviews in Clinical Laboratory Sciences·D H Russell
Jan 1, 1981·Critical Reviews in Clinical Laboratory Sciences·J R ShipeM R Wills
Jul 1, 1982·Journal of Endocrinological Investigation·A CastiS Bernasconi
Jan 1, 1976·Annals of Clinical Biochemistry·A M Neville, E H Cooper


Aug 1, 1968·Proceedings of the National Academy of Sciences of the United States of America·D H Russell, S H Snyder
Mar 1, 1971·Proceedings of the National Academy of Sciences of the United States of America·D H Russell
Jun 1, 1966·Proceedings of the National Academy of Sciences of the United States of America·A Raina, S S Cohen
Jul 20, 1966·Biochimica Et Biophysica Acta·A RainaM Siimes

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