PMID: 3746529Sep 1, 1986Paper

Urinary sIgA in children with urinary tract infection

The Journal of Pediatrics
M FliednerE Ritz

Abstract

Urinary secretory IgA (sIgA) was measured using a specific ELISA with insolubilized anti-IgA and enzyme-linked antisecretory component. This test was applied to unprocessed urine from healthy children and from children with urinary tract infection. Normal range was a function of age. In 175 healthy children the excretion rate of sIgA was low in infants younger than 6 months but was constant between ages 6 months to 15 years (median 0.69 mg/gm creatinine, range 0.15 to 3.4 mg/gm creatinine), whereas sIgA concentration (milligrams per liter of urine) increased continuously with age. No sex difference was noted. There were no significant circadian changes or day-to-day variability. Thirty girls, age 1 to 16 years, were examined; they had a history of recurrent symptomatic episodes of urinary tract infection but had anatomically normal tracts and no symptoms, and no bacteriuria at the time of study. sIgA excretion rate was significantly lower (0.45 mg/gm, creatinine, 0.08 to 0.75 mg/gm creatinine) than in controls. In contrast, 11 girls examined at the time of symptomatic urinary tract infections, and who had normal urinary tracts, had significantly (P less than 0.01) higher sIgA excretion rates (1.4 mg/gm creatinine, 0.8 to 3.4 mg...Continue Reading

References

Nov 2, 1978·The New England Journal of Medicine·M H Mulks, A G Plaut
Apr 1, 1985·Scandinavian Journal of Immunology·C Svanborg EdénJ Mestecky
Sep 7, 1972·The New England Journal of Medicine·T B Thomasi
May 1, 1983·Kidney International·G RiedaschE Ritz

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Citations

Jul 1, 1993·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·M G Morgan, H McKenzie
Sep 7, 2007·Journal of Molecular Medicine : Official Organ of the Gesellschaft Deutscher Naturforscher Und Ärzte·Milan Chromek, Annelie Brauner
Jun 2, 2007·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Vesna D StojanovićJelena D Bubalo
Dec 1, 2001·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·E SumanB M Hegde
Aug 1, 1987·Archives of Disease in Childhood·A Prentice
Jan 1, 1989·Clinical Radiology·T Ben-AmiM Hertz
May 29, 1999·Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Médicas E Biológicas·M R Teodósio, E C Oliveira
Jul 1, 1995·International Journal of Urology : Official Journal of the Japanese Urological Association·A TeraiO Yoshida
Oct 21, 2005·Journal of the American Society of Nephrology : JASN·James C RiceBogdan J Nowicki
Jan 1, 1992·Annals of Tropical Paediatrics·U K Kala, D W Jacobs
Jul 1, 1991·The Journal of Urology·D T UehlingE Balish
Jan 10, 2018·BMC Infectious Diseases·Ibrahim H BabikirIshag Adam
Jul 1, 1996·Clinical and Diagnostic Laboratory Immunology·D CohenJ Shemer

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