PMID: 9164681May 1, 1997Paper

Urinary steroids at time of surgery in postmenopausal women with breast cancer

Breast Cancer Research and Treatment
S JuricskayK Kett

Abstract

Urinary steroid metabolites were measured by capillary gas chromatography in 22 postmenopausal women with operable breast cancer on day before the tumour excision and in 20 hospitalised control who were before an operation from other cause than cancer. Serum dehydroepiandrosterone-sulphat (DHEAS) and testosterone (T) level were measured by radioimmunassay in the same groups and same time. There was no significant difference in the level of urinary androgen metabolites. Pregnanediol level was significantly lower (P < 0.05) in cancer patients. In the 5 patients with positive axillary nodes the tetrahydrocortisol and alpha-cortolone levels were significantly (P < 0.05) higher than in node negative ones. There was no significant differences in the serum DHEAS and T levels. These results indicate that metabolic changes are existing in postmenopausal patients which may be a cause or a consequence of the disease.

References

May 22, 1976·Lancet·I J McFadyenK Griffiths
Apr 1, 1992·International Journal of Cancer. Journal International Du Cancer·J B Adams
Mar 1, 1992·The Journal of Steroid Biochemistry and Molecular Biology·Y Mousavi, H Adlercreutz
Jan 1, 1991·Journal of Clinical Epidemiology·A MicheliF Berrino
Jan 1, 1988·European Journal of Cancer & Clinical Oncology·T J Key, M C Pike
Oct 1, 1985·European Journal of Cancer & Clinical Oncology·P HillF Kasumi
Jan 3, 1980·The New England Journal of Medicine·I C Henderson, G P Canellos
Jan 1, 1994·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·R A BadweR D Rubens
Jan 1, 1994·Breast Cancer Research and Treatment·Y S López-BoadoC López-Otín
Jan 1, 1993·Breast Cancer Research and Treatment·P BalleriniG Secreto
Jan 1, 1993·Epidemiologic Reviews·L Bernstein, R K Ross
Apr 1, 1993·The Journal of Steroid Biochemistry and Molecular Biology·J R Pasqualini
Jan 1, 1993·Tumour Biology : the Journal of the International Society for Oncodevelopmental Biology and Medicine·M H LiberatoM M Brentani

❮ Previous
Next ❯

Citations

Sep 19, 2009·Journal of Advanced Nursing·Tsu-Yin Wu, David Ronis

❮ Previous
Next ❯

Related Concepts

Related Feeds

Breast Cancer: Chemo-Resistance

Some cancers are difficult to treat and aggressive including the "triple-negative" breast cancer. This type of cancer is chemoresistant even before chemotherapy begins. Here are the latest discoveries chemo-resistance in breast cancer.

Cancer Metabolism

In order for cancer cells to maintain rapid, uncontrolled cell proliferation, they must acquire a source of energy. Cancer cells acquire metabolic energy from their surrounding environment and utilize the host cell nutrients to do so. Here is the latest research on cancer metabolism.

Related Papers

European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)
R A BadweR D Rubens
© 2021 Meta ULC. All rights reserved