Urinary sucrose and fructose as biomarkers of sugar consumption: comparison of normal weight and obese volunteers.

International Journal of Obesity : Journal of the International Association for the Study of Obesity
A M C P JoosenSheila Bingham

Abstract

Using urinary sugars as a biomarker of consumption, we have previously shown that obese people consume significantly more sugars than individuals of normal weight. However, there is concern that recovery of this biomarker may differ between normal weight and obese individuals. A total of 19 subjects, divided into two groups according to their body mass index (BMI) (normal weight BMI < or = 25 kg/m(2), n=10; obese BMI > or = 30 kg/m(2), n=9), participated in a randomized crossover dietary intervention study of three diets providing 13, 30 and 50% of energy from sugars for 4 days each while living in a volunteer suite. The mean urinary sucrose and fructose excretions in 24-h urine increased with increasing sugar consumption over the three dietary periods in both BMI groups and were significantly different between the diets (P < 0.01). There was no significant interaction effect of BMI class on the mean urinary excretions of these sugars with different sugar intakes, either as absolute values or expressed as a percentage of total sugar intake. In conclusion, BMI does not affect the validity of sucrose and fructose excretions in 24-h urine collections used as biomarkers to estimate total sugar consumption.

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Citations

Apr 10, 2009·Human Genetics·Mazda JenabSheila A Bingham
Dec 15, 2012·Nutrition Journal·Valisa E HedrickBrenda M Davy
Feb 22, 2012·Journal of the Science of Food and Agriculture·Gunter G C Kuhnle
May 28, 2016·Pflügers Archiv : European journal of physiology·Olga VitavskaHelmut Wieczorek
Jul 18, 2015·Nutrients·Natasha Tasevska
Aug 19, 2010·European Journal of Clinical Nutrition·S A JohnerT Remer
Jan 1, 2020·Electrophoresis·Naresh Kumar ManiSuman Chakraborty
May 4, 2016·Current Opinion in Clinical Nutrition and Metabolic Care·Brenda Davy, Hope Jahren
Sep 23, 2014·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Natasha TasevskaVictor Kipnis
Feb 1, 2011·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Natasa TasevskaVictor Kipnis
Oct 2, 2020·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Taymara C AbreuJeanne H M de Vries
Jan 20, 2021·European Journal of Nutrition·Ines PerrarUte Alexy

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