Abstract
The aim of this study was to analyze antibiotic resistance and virulence patterns in Pseudomonas aeruginosa (PAR) isolates from urinary tract infections among children in Southern Poland. This study comprised consecutive, non-repetitive PAR isolates sent from two collaborative laboratories. The study group consisted of children aged up to 17 years from Southern Poland with culture-proven PAR UTIs. Relevant information about patients with UTIs, such as age, sex, and type of infection (polymicrobial or monomicrobial), was collected. Isolates were screened for major virulence factors found in uropathogenic PAR strains. Multidrug-resistant (MDR) strains were defined as strains not susceptible to one antimicrobial in at least three different antimicrobial classes. Extensively drug resistant (XDR) strains were defined as strains susceptible to no more than two antimicrobial classes. The total prevalence of PAR UTIs was 2.1%, and in children <5 years of age it was 3.0%. A total of 26 isolates was tested: 21 from outpatients and five from inpatients. Most infections (80.8%) occurred in children ≤ 4 years of age. The most prevalent virulence gene was exoY (96.2%). The prevalence of other effector proteins was 88.5% for exoT, 92.3% for e...Continue Reading
References
Nov 20, 1998·Journal of Tropical Pediatrics·U C Ozumba
Dec 3, 1999·The Journal of Hospital Infection·K P RumbaughA N Hamood
Sep 2, 2000·The Journal of Antimicrobial Chemotherapy·G Kahlmeter
Feb 26, 2003·Disease-a-month : DM·Allan Ronald
Jul 10, 2003·Infectious Disease Clinics of North America·Kalpana Gupta
Aug 9, 2003·Journal of Clinical Microbiology·Temitayo AjayiJeanine P Wiener-Kronish
Dec 8, 2004·Journal of Clinical Microbiology·Shirley FinnanE Fidelma Boyd
Feb 26, 2005·Infection and Immunity·Russell E VanceJohn J Mekalanos
Feb 27, 2008·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Michael GoldmanGalia Grisaru-Soen
Sep 17, 2008·Infection·N MarcusG Livni
Aug 14, 2009·Journal of Clinical Microbiology·Vered SchechnerShiri Navon-Venezia
Jan 5, 2011·International Journal of Medical Microbiology : IJMM·Petra TielenDieter Jahn
Jan 5, 2011·Journal of Paediatrics and Child Health·Gabrielle J WilliamsJonathan C Craig
Nov 26, 2011·The Journal of Urology·M BitsoriE Galanakis
Dec 4, 2012·Expert Review of Anti-infective Therapy·Maria Bitsori, Emmanouil Galanakis
Jan 19, 2013·BMC Infectious Diseases·Inês LinharesAdelaide Almeida
Feb 2, 2013·The Journal of Urology·Rachel S EdlinHillary L Copp
May 21, 2013·Journal of the Pediatric Infectious Diseases Society·Kevin W DahlePer Hans Gesteland
Jul 1, 2010·Brazilian Journal of Microbiology : [publication of the Brazilian Society for Microbiology]·Ivan MitovBoyka Markova
Jun 25, 2014·International Journal of Pediatrics·Seyed Reza MirsoleymaniMojtaba Mehtarpoor
Citations
Jun 30, 2016·Microbial Pathogenesis·M S Kumar, A P Das
Oct 12, 2000·American Journal of Infection Control·L CorderoL W Ayers
Sep 20, 2017·Journal of Medical Microbiology·Júlia RadóSándor Szoboszlay
Dec 19, 2019·Veterinary World·A N DapghE A Elgabry
Jun 13, 2017·FEMS Microbiology Letters·John W NewmanJoanne L Fothergill
Jun 10, 2020·Toxins·Brant M WagenerJean-François Pittet
Sep 28, 2018·Frontiers in Microbiology·Fengping LiuYong Q Chen
Sep 14, 2019·Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases·Fatemeh JavanmardiMahrokh Rajaee
Mar 7, 2021·Antibiotics·Tomasz BogielEugenia Gospodarek-Komkowska