Abstract
Extended-spectrum beta-lactamase-expressing Gram-negative bacilli (ESBL-GNB) now commonly cause community-acquired infections, including urinary tract infections (UTI), and represent a challenge for practitioners in choosing empirical antibiotics. The aim of this study was to describe the epidemiology and clinical characteristics of UTIs/bacteriuria due to ESBL-GNB in Australia. At a single-site tertiary referral hospital, 100 cases with UTIs/bacteriuria due to ESBL-GNB were matched to 100 cases where UTIs/bacteriuria were caused by organisms matching the ESBL bacterial species that had routine susceptibility to antibiotics. Potential risk factors for ESBL-GNB UTI/bacteriuria and differences in clinical outcomes were identified. Length of admission prior to positive sample (odds ratio (OR) 1.3, p = 0.03, per week), exposure to antibiotics (OR 5.7, p < 0.001), return from overseas travel (OR 6.5, p = 0.002), and nursing home residency (OR 4.2, p = 0.03) were identified as risk factors associated with ESBL-GNB UTI/bacteriuria in the multivariate analysis. In addition, ESBL-GNB-infected cases subsequently had a longer inpatient stay (median 6 vs. 2 days, p = 0.002) and were admitted to the intensive care unit more frequently (28/1...Continue Reading
References
Nov 1, 1983·Infection·H KnotheS Mitsuhashi
Oct 24, 1998·The Journal of Antimicrobial Chemotherapy·W Brumfitt, J M Hamilton-Miller
Jul 18, 2002·Antimicrobial Agents and Chemotherapy·Eric ViaenePaul M Tulkens
Feb 27, 2004·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·R ColodnerR Raz
Feb 17, 2005·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Lindsay E NicolleUNKNOWN American Geriatric Society
Dec 16, 2006·Urology·Javier EnaConcepción Amador
Nov 26, 2008·Journal of Chemotherapy·E YilmazS Helvaci
Jun 19, 2009·Current Drug Safety·Emilia HardakMordechai Yigla
Jun 16, 2010·Antimicrobial Agents and Chemotherapy·Thomas TängdénElisabeth Löwdin
Aug 5, 2010·The Journal of Antimicrobial Chemotherapy·C D J den HeijerE E Stobberingh
Sep 14, 2010·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·K Kennedy, P Collignon
Nov 16, 2010·Journal of Microbiology, Immunology, and Infection = Wei Mian Yu Gan Ran Za Zhi·Po-Ren HsuehLee-Jene Teng
Nov 9, 2011·The Medical Journal of Australia·Rhonda L StuartTony M Korman
Mar 7, 2012·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·B A RogersD L Paterson
Aug 29, 2012·Antimicrobial Agents and Chemotherapy·Elizabeth A NeunerDavid van Duin
Oct 9, 2012·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Sarah Tschudin-SutterAndreas Franz Widmer
Feb 4, 2014·The Medical Journal of Australia·Kyra Y L ChuaBenjamin P Howden
Citations
Nov 3, 2015·Infectious Diseases·Frederik Boëtius HertzNiels Frimodt-Møller
Dec 25, 2015·Current Infectious Disease Reports·Joseph B CanteySarah M McCormick
Jan 3, 2016·Research in Microbiology·Ahmed K Al AtyaDjamel Drider
Apr 27, 2016·Enfermedades infecciosas y microbiología clínica·Natalia Chacón-MoraElisa Cordero Matía
Oct 30, 2015·World Journal of Urology·Liam TonerSamih Al-Hayek
Jul 5, 2016·Journal of Chemotherapy·Benjamin J EreshefskyCraig A Martin
Aug 10, 2016·Journal of Travel Medicine·Herbert L DuPont, Robert Steffen
Sep 15, 2016·Revista latino-americana de enfermagem·Anna Letícia MirandaCynthia Adalgisa Mesojedovas Aguiar
Dec 31, 2018·The American Journal of Tropical Medicine and Hygiene·Rania Y ShashAshraf A Mosharafa
Oct 2, 2019·Geriatrics & Gerontology International·Ana B Gómez BeldaArturo Artero
Apr 30, 2019·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Anu KanteleJames R Johnson
Feb 15, 2019·BMC Infectious Diseases·Helena Kornfält IsbergAnders Beckman
Sep 19, 2019·International Journal of Clinical Practice·Feizollah MansouriMandana Afsharian
Sep 9, 2017·Journal of Travel Medicine·Herbert L DuPont, Robert Steffen
Apr 25, 2020·Antibiotics·Sabrina Morris, Elizabeth Cerceo
May 23, 2020·The Journal of Antimicrobial Chemotherapy·Adam G StewartDavid L Paterson
Mar 27, 2018·International Journal of Nursing Practice·Hui Ang, Xuan Sun
Jan 15, 2019·Investigative and Clinical Urology·Eda KoksalGunay Ertem
Jul 2, 2019·Therapeutic Advances in Infectious Disease·Luka Bielen, Robert Likic
Jun 3, 2017·Applied Biochemistry and Biotechnology·Rajamohamed Beema ShafreenSulaiman Ali Alharbi
Jan 27, 2017·The Journal of Antimicrobial Chemotherapy·Iftihar KoksalSibylle Lob
Feb 23, 2019·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Aurélien Emmanuel MartinezSarah Tschudin-Sutter
Aug 31, 2020·Infection·Zhuoxin PengBette Liu
May 19, 2017·Journal of Travel Medicine·Paul-Louis WoertherAnu Kantele
Nov 2, 2017·Antimicrobial Resistance and Infection Control·Vimalanand S PrabhuAnirban Basu
Jul 1, 2018·Current Infectious Disease Reports·Kevin L Schwartz, Shaun K Morris
Sep 6, 2017·International Journal of Clinical Practice·Arturo ArteroJosé M Eiros
Oct 17, 2018·Journal of Paediatrics and Child Health·Jus RakhraHasantha Gunasekera
Jan 12, 2021·Saudi Journal of Biological Sciences·Jamal M KhaledN Manoharan
Jun 12, 2021·The Journal of Infection·Jingjing QuanYunsong Yu
Jun 16, 2021·BMC Infectious Diseases·Marion OpatowskiLaurence Watier
Jun 22, 2021·Access Microbiology·Kuma DiribaAsrat Anja