Urine analysis by laser Raman spectroscopy

Lasers in Surgery and Medicine
W R PremasiriM E Womble

Abstract

We examine the use of Raman spectroscopy to analyze components in human urine. Targeted urine components include urea, uric acid, and creatinine. Urea concentration in urine is sufficiently high that normal Raman spectroscopy may be used for its analysis. All other components are in low concentrations requiring the use of surface-enhanced Raman spectroscopic methods (SERS). Both normal Raman and SERS approaches have been investigated for total urine-nitrogen determination, urine urea-nitrogen determination, and for the urea/creatinine excretion ratio.

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Citations

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