Urine ketone dip test as a screen for ketonemia in diabetic ketoacidosis and ketosis in the emergency department

Annals of Emergency Medicine
G W HendeyT C Soliz

Abstract

To determine the sensitivity of the urine ketone dip test (UKDT) for the detection of ketonemia in patients with diabetic ketoacidosis (DKA) and diabetic ketosis (DK) in the ED. We conducted a retrospective chart review in the ED of an urban, university-affiliated county teaching hospital. The study population comprised patients seen in the ED during 1994 and 1995 with a discharge diagnosis of DKA or DK and underwent urinalysis within 4 hours of the initial serum electrolyte and ketone determinations. We calculated test sensitivity, along with 95% confidence intervals (CIs). One hundred forty-eight patients with 223 occurrences diagnosed as DKA or DK were seen in the ED during the study period. One hundred fourteen patients with 146 occurrences of DKA or DK met all inclusion criteria; these patients made up the study group. There were 99 cases of DKA and 47 cases of DK. The sensitivity of the UKDT for the detection of ketonemia in all patients with DKA or DK was 97% (95% CI, 94% to 99%). In the subgroup of patients with DKA, the sensitivity of the UK was 97% (95% CI, 92% to 99%). For patients with DK, the sensitivity of the UK was 98% (95% CI, 89% to 99%). The UKDT is highly sensitive for the presence of serum ketones in patien...Continue Reading

References

Mar 1, 1982·The Journal of Clinical Endocrinology and Metabolism·M H MacGillivrayP A Schaefer
Jan 1, 1993·Acta Diabetologica·D JenkinsA D Wright

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Citations

Jul 13, 2002·The Journal of Emergency Medicine·Gregory J Fermann, Joe Suyama
Jun 15, 2007·Epilepsia·Roberto CantelloFrancesco Monaco
May 16, 2003·Emergency Medicine Journal : EMJ·R D Hardern, N D Quinn
Dec 23, 2015·Journal of Hepato-biliary-pancreatic Sciences·Toshihiko MayumiKoichi Hirata
Dec 19, 2015·Japanese Journal of Radiology·Toshihiko MayumiKoichi Hirata
Sep 25, 2012·Critical Care Clinics·Martina M CartwrightRichard W Carlson
Aug 25, 1999·Annals of Emergency Medicine·T M SchwabT C Soliz
Nov 24, 2004·Endocrine Research·Firat BektasHalide Akbas

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