PMID: 8598964Mar 1, 1996Paper

Uriscreen, a rapid enzymatic urine screening test: useful predictor of significant bacteriuria in pregnancy

Obstetrics and Gynecology
Z HagayV Insler

Abstract

To establish the reliability of a new rapid enzymatic screening test, the Uriscreen, in the detection of significant bacteriuria in pregnancy. During a 6-month period, from July 1 to December 30, 1993, 313 consecutive pregnant patients were evaluated. Randomly voided, midstream, clean-catch urine specimens were used. Each sample was tested by routine laboratory culture and four rapid screening tests: the nitrite and leukocyte esterase dipstick, microscopic examination for pyuria, and the Uriscreen test. Results of the four rapid tests were compared with those of the urine culture. Twenty-four women (7.6%) had urine culture results indicating significant bacteriuria. The sensitivity of the nitrite test, the leukocyte esterase test, and a microscopic examination for pyuria was low (37, 52, and 56%, respectively). The Uriscreen test showed very high sensitivity (100%), lower specificity (81%), a high predictive value of negative results (100%), and a low positive predictive value (30%). The Uriscreen test is a reliable alternative to culture screening of all pregnant patients. A policy of performing a urine culture during pregnancy only on patients with a positive Uriscreen test will save as much as 80% of unnecessary cultures.

References

Dec 15, 1985·American Journal of Obstetrics and Gynecology·G P MarquetteJ R Niebyl
Sep 1, 1993·British Journal of Obstetrics and Gynaecology·I J Etherington, D K James

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Citations

Mar 22, 2000·Obstetrics and Gynecology·L MillarJ Killeen
Mar 1, 1997·Infectious Disease Clinics of North America·L K Millar, S M Cox
Nov 3, 2010·Journal of Veterinary Internal Medicine·D RaboissonF Schelcher
Jun 4, 2004·BMC Urology·Walter L J M DevilléLex M Bouter
Oct 31, 2001·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·E BouzaUNKNOWN Co-operative Group of the European Study Group on Nosocomial Infections
Jul 1, 1997·Journal of Obstetric, Gynecologic, and Neonatal Nursing : JOGNN·B J PolivkaJ R Wilkins
Aug 3, 2013·Clinica Chimica Acta; International Journal of Clinical Chemistry·M H M MartinezC R Garlipp
Aug 2, 2006·American Journal of Clinical Pathology·Andrew St JohnChristopher P Price
Jan 5, 2005·Journal of the Society for Gynecologic Investigation·Roberto J Teppa, James M Roberts
Oct 30, 2015·British Journal of Biomedical Science·S Ahmad
Dec 10, 1999·The Urologic Clinics of North America·A Connolly, J M Thorp

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