Urodynamic risk factors for renal dysfunction in men with obstructive and nonobstructive voiding dysfunction

The Journal of Urology
C V ComiterS V Valla

Abstract

Urodynamic investigation of men with lower urinary tract symptoms, usually attributed to benign prostatic hyperplasia, often reveals bladder outlet obstruction, detrusor instability and/or diminished vesical compliance. We investigated whether these urodynamic abnormalities alone or in combination contribute to renal dysfunction. A total of 161 men with lower urinary tract symptoms was evaluated by urodynamics, and outlet obstruction, detrusor instability and decreased compliance (30 ml./cm. water or less) were noted. Serum blood urea nitrogen (BUN) and creatinine were measured. Cases were categorized according to the urodynamic diagnosis. Mean values of serum BUN and creatinine as well as the incidence of elevated BUN and creatinine were compared among groups. Of the cohort 54 men (34%) had elevated BUN and 19 (12%) had elevated serum creatinine. No significant correlation was found between the degree of obstruction and BUN or creatinine level. Mean serum BUN and creatinine, and the incidence of abnormal laboratory tests did not significantly differ among those with outlet obstruction, detrusor instability, both conditions or neither condition. However, in patients with outlet obstruction and detrusor instability there was a s...Continue Reading

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Citations

Feb 16, 2005·The Journal of Urology·Andrew D RuleSteven J Jacobsen
Jun 15, 2010·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Stein Ivar HallanPaul Stevens
Mar 15, 2012·Neurourology and Urodynamics·Matthias OelkeJohn Heesakkers
May 17, 2015·Diabetes Research and Clinical Practice·A Jin ChoJung Woo Noh
Apr 26, 2003·Der Urologe. Ausg. A·R BergesUNKNOWN DGU-Leitlinienkommission
Oct 13, 2006·Current Opinion in Urology·A W Thomas, P Abrams
Sep 5, 2020·Neurourology and Urodynamics·Sanjay Sinha, Lavina Matai
Jul 22, 2017·Current Urology Reports·John T Stoffel
Nov 8, 2020·International Journal of Urology : Official Journal of the Japanese Urological Association·Yariv Stabholz, Jaspreet S Sandhu

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