PMID: 6107911Aug 1, 1980Paper

Urotensin II: a somatostatin-like peptide in the caudal neurosecretory system of fishes

Proceedings of the National Academy of Sciences of the United States of America
D PearsonH A Bern

Abstract

Urotensin II, a peptide hormone from the caudal neurosecretory system of the teleost, Gillichthys mirabilis, was isolated by using classical chromatographic techniques and high-performance liquid chromatography (HPLC). Direct microtechniques for sequence determination were used to establish its structure. Urotensin II from Gillichthys is a 1363-dalton dodecapeptide with the amino acid sequence Ala-Gly-Thr-Ala-Asp-Cys-Phe-Trp-Lys-Tyr-Cys-Val. This sequence is homologous with somatostatin in positions 1 and 2 and 7-9. The sequence has been verified by the production of a bioactive synthetic urotensin II. The possible chemical and physiological significance of its homology to somatostatin is discussed.

References

Jun 1, 1978·Proceedings of the National Academy of Sciences of the United States of America·D F VeberR Hirschmann
Mar 1, 1978·General and Comparative Endocrinology·D K ChanH A Bern
Jul 22, 1975·Biochemical and Biophysical Research Communications·M BrownR Guillemin
Nov 1, 1977·Biochemistry·L A HolladayD Puett
Apr 1, 1976·Proceedings of the National Academy of Sciences of the United States of America·L A Holladay, D Puett
Jul 22, 1975·Biochemical and Biophysical Research Communications·J RivierW Vale
Sep 1, 1972·Proceedings of the Society for Experimental Biology and Medicine·F Lacanilao, H A Bern
Feb 1, 1980·Science·M W Hunkapiller, L E Hood

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Citations

May 5, 2000·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·D E Newby, R Jalan
Jan 1, 1990·The Journal of Experimental Zoology. Supplement : Published Under Auspices of the American Society of Zoologists and the Division of Comparative Physiology and Biochemistry·C A Loretz
Dec 3, 1999·Biochemical and Biophysical Research Communications·Q LiuC T Caskey
Nov 5, 2004·Naunyn-Schmiedeberg's Archives of Pharmacology·Raffaella VerguraDomenico Regoli
Apr 28, 2010·Naunyn-Schmiedeberg's Archives of Pharmacology·Benjamin D HuntDavid G Lambert
Nov 13, 2012·Fish Physiology and Biochemistry·Magdalena GozdowskaEwa Kulczykowska
Mar 17, 2007·Current Hypertension Reports·Henry Krum, Will Kemp
Apr 27, 1988·European Journal of Pharmacology·H ItohK Lederis
Jan 1, 1989·Pharmacology & Therapeutics·S Nilsson, S Holmgren
Jan 1, 1985·Peptides·M C Thorndyke, T J Shuttleworth
Oct 1, 1993·Progress in Neurobiology·L H Lazarus, M Attila
Feb 1, 1994·The Journal of Steroid Biochemistry and Molecular Biology·M FeuilloleyH Vaudry
Mar 18, 2004·Neuroscience Letters·Yoshio MatsumotoMasahiko Fujino
Dec 7, 2002·Regulatory Peptides·Thomas DschietzigKarl Stangl
May 18, 2001·Neuroscience Letters·S L DunN J Dun
Nov 5, 2002·Bioorganic & Medicinal Chemistry·Paolo GriecoPaolo Rovero
Apr 26, 2003·Organic Letters·Fabio BertozziRoger Olsson
Aug 22, 2000·British Journal of Pharmacology·F E BottrillR White
Jan 12, 2002·British Journal of Pharmacology·Felix Böhm, John Pernow
Sep 19, 2002·British Journal of Pharmacology·Valeria CamardaDomenico Regoli
Oct 17, 2002·British Journal of Pharmacology·Janet J Maguire, Anthony P Davenport
Nov 8, 2002·Journal of Neurochemistry·Catalin M FilipeanuNae J Dun
Jan 1, 1984·Proceedings of the National Academy of Sciences of the United States of America·A GibsonJ H Botting
Sep 1, 1986·Proceedings of the National Academy of Sciences of the United States of America·C R Yulis, K Lederis
Jul 14, 2010·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Ari MosenkisRaymond R Townsend
Apr 17, 2008·Cardiology in Review·Nirav DesaiWilliam H Frishman

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