Urothelial cancer biomarkers for detection and surveillance

Urology
Louis S Liou

Abstract

Cancer is a complex process, and the US cancer-specific death rate has not changed in the last 50 years. Cure of the disease usually results from early diagnosis and treatment. Urothelial carcinoma (UC) has the highest recurrence rate of any cancer and is the second most common cancer of the genitourinary tract. It usually does not present at a metastatic stage, but only 50% of patients treated with cystectomy survive > or =5 years. There is a UC surveillance protocol, which includes cystoscopy, imaging, and cytology, to detect progression and allow early treatment of life-threatening UC. Many patients may not complete the surveillance protocol, and the cost of these studies is increasing. In addition, questions about the efficacy of these modalities have been raised. Therefore, bladder urinary tumor markers have been developed to aid in the diagnosis and surveillance of UC. Because urothelial cells are bathed in the urine and are continually shed, UC presents a unique opportunity to monitor bladder neoplasia in a noninvasive fashion. Currently, there are many research bladder tumor markers, but only a few are commercially available US Food and Drug Administration (FDA)-approved products. The commercially available bladder tumo...Continue Reading

References

Jan 1, 1987·British Journal of Urology·R EwingJ W Hetherington
Jun 8, 2000·Clinica Chimica Acta; International Journal of Clinical Chemistry·P Voswinckel
Jan 6, 2001·Scandinavian Journal of Urology and Nephrology. Supplementum·C Cordon-CardoG Sauter
Feb 15, 2001·The Journal of Urology·B R Konety, R H Getzenberg
Aug 21, 2001·Journal of Insurance Medicine·M Moore
Oct 11, 2002·Nature·Bruce R Zetter, Jacqueline Banyard
Oct 24, 2002·Clinical Chemistry and Laboratory Medicine : CCLM·Eric Barlandas-RendónAngelika Heinschink
Apr 17, 2003·Journal of the National Cancer Institute·Deborah SchragColin B Begg
Aug 6, 2003·Critical Reviews in Oncology/hematology·Michael A SimonMark S Soloway
Jan 10, 2004·The Journal of Urology·Shahrokh F ShariatSeth P Lerner
Jan 22, 2004·European Urology·J A Witjes
Feb 24, 2004·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·Thu-Suong Van LeRobert H Getzenberg
Jul 6, 2004·Clinical Biochemistry·Marta Sanchez-Carbayo
Sep 25, 2004·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·Bernard TêtuYves Fradet
Feb 17, 2005·JAMA : the Journal of the American Medical Association·H Barton GrossmanYu Shen
Jun 11, 2005·The Journal of Urology·Marcus L QuekDonald G Skinner
Jul 23, 2005·Urologia Internationalis·Giacomo NovaraWalter Artibani

❮ Previous
Next ❯

Citations

May 26, 2012·Urology Annals·Mahmoud Alameddine, Anmar Nassir
Dec 7, 2007·World Journal of Urology·Carvell T Nguyen, J Stephen Jones
Dec 20, 2007·World Journal of Urology·Piyush K AgarwalAshish M Kamat
Apr 22, 2009·Expert Review of Molecular Diagnostics·Wun-Jae Kim, Yong-June Kim
Jul 1, 2008·Expert Review of Anticancer Therapy·Samir P Shirodkar, Vinata B Lokeshwar
Jun 1, 2008·Expert Opinion on Medical Diagnostics·Dionisios MitropoulosPetros Perimenis
Mar 16, 2011·Progrès en urologie : journal de l'Association française d'urologie et de la Société française d'urologie·G PignotV Ravery
Jul 22, 2008·The Journal of Urology·Eun-Jung KimWun-Jae Kim
Feb 5, 2008·Urology·Y Mark Hong, Kevin R Loughlin
Jul 14, 2007·Urologic Oncology·Seth P LernerAdam S Kibel
Mar 27, 2007·The Journal of Urology·Ofer YossepowitchS Machele Donat
Apr 25, 2009·International Journal of Urology : Official Journal of the Japanese Urological Association·Susumu KageyamaTatsuhiro Yoshiki
Aug 30, 2008·International Journal of Urology : Official Journal of the Japanese Urological Association·Young Kyoon Kim, Wun-Jae Kim
Jul 1, 2008·Proteomics. Clinical Applications·Pavel GromovJulio E Celis
Apr 7, 2009·Cancer·Susana FerraOscar Lin
Oct 26, 2011·International Journal of Cancer. Journal International Du Cancer·Yun-Sok HaWun-Jae Kim
Apr 6, 2011·Cytometry. Part a : the Journal of the International Society for Analytical Cytology·Gabor PajorNorbert Sule
Sep 9, 2010·International Journal of Cancer. Journal International Du Cancer·Reza R SerizawaPer Guldberg
Mar 11, 2015·Journal of Cellular and Molecular Medicine·Zhenming JiangXi Chen
Mar 15, 2014·Tumour Biology : the Journal of the International Society for Oncodevelopmental Biology and Medicine·Wen ChengLi-Ming Zhou
Jul 6, 2014·The Journal of Urology·Noa DavisOfer Yossepowitch
Feb 23, 2018·The Analyst·Puja Sandbhor Gaikwad, Rinti Banerjee
Jun 19, 2018·Expert Review of Molecular Diagnostics·Alessia CimadamoreRodolfo Montironi
Feb 15, 2020·Investigative and Clinical Urology·Jayoung KimWun-Jae Kim
Aug 15, 2006·Current Opinion in Urology

❮ Previous
Next ❯

Related Concepts

Related Feeds

Bladder Carcinoma In Situ

Bladder Carcinoma In Situ is a superficial bladder cancer that occurs on the surface layer of the bladder. Discover the latest research on this precancerous condition in this feed.

Related Papers

Critical Reviews in Oncology/hematology
Michael A SimonMark S Soloway
JAMA : the Journal of the American Medical Association
H Barton GrossmanYu Shen
Expert Review of Anticancer Therapy
Samir P Shirodkar, Vinata B Lokeshwar
© 2021 Meta ULC. All rights reserved