Ursane-type triterpenoid saponins from Elsholtzia bodinieri

Natural Product Research
Lunli XiangJin-Dong Zhong

Abstract

Investigation of the n-BuOH extract of the aerial parts of Elsholtzia bodinieri led to the isolation of two new ursane-type triterpenoid saponins, bodiniosides O (1) and P (2), along with five known saponins, rotungenoside (3), 3,28-O-bis-β-d-glucopyranosides of 19α-hydroxyarjunolic acid (4), oblonganosides I (5), rotungenic acid 28-O-α-L-rhamnopyranosyl-(1→2)-β-d-glucopyranoside (6), and bodinioside M (7) isolated from the species. The structures of compounds 1 and 2 were characterized by spectroscopic data as well as acid hydrolysis and GC analysis as 3-O-β-d-xylopyranosyl-23-acetoxy-urs-12(13)-en-28-oic acid 28-O-β-d-xylopyranosyl-(1→6)-[β-d-glucopyranosyl-(1→4)-α-L-rhamnopyranosyl-(1→2)]-β-d-glucopyranoside and 3-O-β-d-xylopyranosyl-23-hydroxy-urs-12(13)-en-28-oic acid 28-O-β-d-glucopyranosyl-(1→6)-β-d-glucopyranoside. Compounds 1 and 2 exhibited potent anti-HCV activities in vitro with a selective index of 30.63 and 9.08, respectively.

References

Feb 6, 2007·Journal of Agricultural and Food Chemistry·Zu-Jian WuJian-Guo Shen
Apr 2, 2008·Chemical & Pharmaceutical Bulletin·Rong-Tao LiHan-Dong Sun
Dec 12, 2012·Chemistry Central Journal·Zhiqin GuoGaimei She
Apr 20, 2016·Natural Product Research·Jin-Dong ZhongRong-Tao Li
May 4, 2016·Archives of Pharmacal Research·Jin-Dong ZhongRong-Tao Li

❮ Previous
Next ❯

Citations

Feb 8, 2020·Natural Product Research·Linyao YangJindong Zhong

❮ Previous
Next ❯

Methods Mentioned

BETA
NMR
glycosidation

Related Concepts

Related Feeds

Antivirals

Antivirals are medications that are used specifically for treating viral infections. Discover the latest research on antivirals here.

Antivirals (ASM)

Antivirals are medications that are used specifically for treating viral infections. Discover the latest research on antivirals here.