US Elastography Using Carotid Artery Pulsation May Increase the Diagnostic Accuracy for Thyroid Nodules with US-Pathology Discordance

Ultrasound in Medicine & Biology
Yoon Joo ChoJin Wook Choi

Abstract

This study evaluated the diagnostic performance of ultrasound elastography (USE) using carotid arterial pulsation and determined the reproducibility of USE for thyroid nodules. A total of 148 patients with 173 thyroid nodules participated. The mean elasticity contrast index (ECI) was significantly higher in malignant nodules (3.1 ± 1.5) than in benign nodules (1.7 ± 0.8) (p < 0.001). When a cut-off ECI value of 3.5 was used, the diagnostic accuracy (78.6%) of gray-scale ultrasound (US) + ECI was the highest compared with that of the gray-scale US (76.9%) and ECI (67.1%). In 16 of 43 nodules (37.2%) with US-pathology, discordance could be correctly reclassified as benign (8 of 11) or malignant (8 of 32). The intra-class correlation coefficient for inter-observer agreement was 0.96, and those for intra-observer agreement were 0.97 and 0.98. Thyroid nodules with ECI values of >3.5 may have an additional value to increase the diagnostic accuracy for nodules with US-pathology discordance with reproducible results.

Citations

Jan 30, 2019·Ultrasonography·Chong-Ke Zhao, Hui-Xiong Xu
Mar 14, 2019·Journal of Korean Medical Science·Hyun Soo ParkUNKNOWN Korean Society of Ultrasound in Obstetrics and Gynecology Research Group
Feb 11, 2020·Frontiers in Endocrinology·Dario TuminoFabio Maino
Sep 4, 2018·Korean Journal of Radiology : Official Journal of the Korean Radiological Society·Soo Yeon HahnKo Woon Park

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