Use of [18F]fluorodeoxyglucose positron emission tomography in evaluating locally recurrent and metastatic adrenocortical carcinoma

The Journal of Clinical Endocrinology and Metabolism
Gavin MackieD E Schteingart

Abstract

Adrenocortical carcinomas are uncommon, and their evaluation by [(18)F]fluorodeoxyglucose positron emission tomography (FDG PET) has not been well evaluated. The purpose of this study was to examine the potential utility of FDG PET in the detection of recurrent or metastatic adrenocortical carcinoma. In patients with known adrenocortical carcinoma who underwent FDG-PET imaging for suspected recurrence or metastasis, FDG activity was compared with other imaging findings, clinical features, and the presence or absence of disease as confirmed by resection, biopsy, or clinical follow-up. The study took place at four tertiary referral centers. Twelve patients (10 females and two males, 5-71 yr of age) were evaluated. The main outcome measures were FDG activity, other imaging findings, and clinical features. Abnormal FDG uptake correctly indicated tumor recurrence in 10 patients. One patient with no abnormal FDG activity had a morphological abnormality subsequently proven to be a postoperative scar. Two patients, one with very small pulmonary lesions and one with a hepatic metastasis, had false-negative findings. Most adrenocortical carcinomas accumulate and retain FDG and thus can be visualized by PET. However, false-negative findin...Continue Reading

References

Nov 1, 1992·Radiology·D G MitchellM M Miettinen
Apr 26, 1990·The New England Journal of Medicine·J P LutonP Blondeau
Feb 8, 1996·International Journal of Cancer. Journal International Du Cancer·A W HsingJ F Fraumeni
Mar 1, 1996·AJR. American Journal of Roentgenology·M KorobkinE A Kazerooni
Mar 10, 1998·AJR. American Journal of Roentgenology·M KorobkinF Londy
Jul 9, 1999·AJR. American Journal of Roentgenology·S MaureaM Salvatore
Sep 27, 2001·World Journal of Surgery·A P DackiwD B Evans
Oct 18, 2001·Cancer Biotherapy & Radiopharmaceuticals·A BechererK Kletter
Mar 14, 2003·European Journal of Nuclear Medicine and Molecular Imaging·Tanweera S KhanBarbro Eriksson
Jun 16, 2004·European Journal of Nuclear Medicine and Molecular Imaging·Georg ZettinigKurt Kletter

❮ Previous
Next ❯

Citations

Nov 15, 2011·Hormones & Cancer·Désirée DeandreisEric Baudin
Feb 22, 2008·Clinical Nuclear Medicine·Isaac BinkovitzLarry Binkovitz
Aug 12, 2009·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Irina VeytsmanTito Fojo
Oct 23, 2012·Indian Journal of Endocrinology and Metabolism·Punit Sharma, Rakesh Kumar
Mar 19, 2014·Nature Reviews. Endocrinology·Barbra S Miller, Gerard M Doherty
May 2, 2014·Journal of Medical Case Reports·Mine AdasTamer Aydin
Jul 24, 2014·AJR. American Journal of Roentgenology·Aisheng DongYushu Bai
May 29, 2014·International Journal of Surgery·Giacomo BenassaiGennaro Quarto
Jul 6, 2014·European Journal of Nuclear Medicine and Molecular Imaging·Satoshi TakeuchiHubert H Chuang
Sep 14, 2010·Best Practice & Research. Clinical Endocrinology & Metabolism·Raul C RibeiroGerard P Zambetti
Jun 9, 2009·Best Practice & Research. Clinical Endocrinology & Metabolism·Martin Fassnacht, Bruno Allolio
Sep 9, 2015·European Journal of Endocrinology·A ArditoM Terzolo
Aug 27, 2010·Clinical Endocrinology·Martin Fassnacht, Bruno Allolio
May 26, 2012·Journal of Surgical Oncology·Clara C Chen, Jorge A Carrasquillo
Jun 9, 2016·Nuclear Medicine and Molecular Imaging·Cristina Rodríguez ReyJosé Luis Carreras Delgado
Dec 21, 2010·Seminars in Oncology·Sanjeeve Balasubramaniam, Tito Fojo
Jan 28, 2006·Nutrition in Clinical Practice : Official Publication of the American Society for Parenteral and Enteral Nutrition·Matthew J Delano, Lyle L Moldawer
Apr 30, 2010·The Journal of Clinical Endocrinology and Metabolism·G RondeauI Bourdeau
Sep 15, 2012·Internal Medicine·Shugo SasakiIichiro Shimomura
Apr 24, 2013·The Journal of Clinical Endocrinology and Metabolism·Michael C KreisslStefanie Hahner
Jan 31, 2016·Clinical Nuclear Medicine·Ka Kit WongMilton D Gross
Jan 16, 2014·Endocrine Reviews·Tobias ElseGary D Hammer
Feb 5, 2009·The Journal of Clinical Endocrinology and Metabolism·Lionel GroussinFlorence Tenenbaum
Oct 2, 2013·The Journal of Clinical Endocrinology and Metabolism·Martin FassnachtBruno Allolio
Apr 4, 2013·Current Opinion in Endocrinology, Diabetes, and Obesity·Isabelle BourdeauAndré Lacroix
Nov 23, 2019·International Journal of Molecular Sciences·Justin D NorthrupMark A Sellmyer
Aug 28, 2020·BMJ Case Reports·Ramon Jr Bagaporo LarrazabalMark Anthony Santiago Sandoval
Jan 8, 2011·European Journal of Clinical Investigation·Ioannis I AndroulakisAshley B Grossman
Jun 15, 2017·Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists·Barbra S MillerUNKNOWN AACE Adrenal Scientific Committee
Nov 1, 2017·World Journal of Clinical Cases·Konstantinos S MylonasKonstantinos P Economopoulos
Oct 1, 2008·PET Clinics·Mohamed HouseniHongming Zhuang
Aug 21, 2007·Seminars in Nuclear Medicine·Hossein JadvarBarry L Shulkin

❮ Previous
Next ❯

Related Concepts

Related Feeds

Adrenocortical Carcinoma

Adrenocortical carcinoma (ACC) is a rare malignancy of the adrenal cortex, associated with a generally dismal prognosis owing to its aggressive behavior. Here are the latest discoveries pertaining to this disease.

Related Papers

European Journal of Nuclear Medicine and Molecular Imaging
Tanweera S KhanBarbro Eriksson
The Journal of Clinical Endocrinology and Metabolism
Martin FassnachtBruno Allolio
The New England Journal of Medicine
Massimo TerzoloAlfredo Berruti
© 2022 Meta ULC. All rights reserved