Use of 51Cr-labeled mononuclear cells for measuring the cellular immune response in mouse lungs.

Infection and Immunity
A ZarkowerF G Ferguson

Abstract

Spleen cells labeled with 51Cr were used in sensitized syngeneic mice to measure the degree of mononuclear cell infiltration into antigen-challenged tissues. With this method, increased cellular infiltration was found after footpad challenge of mice sensitized with sheep erythrocyte, Escherichia coli, and BCG antigens. Cellular response also was determined by using this technique in the lungs of mice sensitized with sheep erythrocytes and BCG. This procedure offers the opportunity to measure cellular infiltration, whether due to cellular or humoral influences, in tissues not easily accessible to conventional immunological manipulation.

References

Jan 1, 1975·Advances in Immunology·A J Crowle
Jan 1, 1977·International Archives of Allergy and Applied Immunology·Y KatsuraI Uesaka
Jan 1, 1975·Annual Review of Physiology·A B Cohen, W M Gold
Jan 1, 1974·Annals of the New York Academy of Sciences·G B Mackaness
Jun 1, 1972·Infection and Immunity·A Zarkower, W Morges
Jan 1, 1974·International Archives of Allergy and Applied Immunology·M J Lefford

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