Use of a Binocular Optical Coherence Tomography System to Evaluate Strabismus in Primary Position.

JAMA Ophthalmology
Reena ChopraPearse A Keane

Abstract

Current clinical methods for assessing strabismus can be prone to error. Binocular optical coherence tomography (OCT) has the potential to assess and quantify strabismus objectively and in an automated manner. To evaluate the use of a binocular OCT prototype to assess the presence and size of strabismus. Fifteen participants with strabismus were recruited in 2016 as part of the EASE study from Moorfields Eye Hospital National Health Service Foundation Trust, London, England, and 15 healthy volunteers underwent automated anterior segment imaging using the binocular OCT prototype. All participants had an orthoptic assessment, including alternating prism cover test (APCT), before undergoing imaging. Simultaneously acquired pairs of OCT images, captured with 1 eye fixating, were analyzed using ImageJ (National Institutes of Health) to assess the presence and angle of strabismus. The direction and size of strabismus measured using binocular OCT was compared with that found using APCT. The median age for participants with strabismus was 55 years (interquartile range [IQR], 33-66.5 years) and for the healthy group, 50 years (IQR, 41-59 years); 15 participants (50%) were women, and 25 participants (83.3%) were white. The median magnitu...Continue Reading

References

Mar 1, 1974·The British Journal of Ophthalmology·P A Graham
Jul 30, 1971·American Journal of Ophthalmology·P E Romano, G K von Noorden
May 1, 1949·American Journal of Ophthalmology·E LUDVIGH
Jan 14, 2009·Archives of Ophthalmology·UNKNOWN Pediatric Eye Disease Investigator Group
Jul 17, 2015·Middle East African Journal of Ophthalmology·Kristina Irsch
Oct 28, 2015·Biomedical Optics Express·Emmanuel ChirrePablo Artal
Jul 22, 2017·Ophthalmology·Konrad P WeberHamish G MacDougall
Aug 22, 2017·Translational Vision Science & Technology·Reena ChopraPearse A Keane

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Citations

Nov 11, 2020·Eye·Reena ChopraPearse A Keane
Apr 3, 2021·Biomedical Optics Express·Ana Rodríguez-AramendíaJosé Luis Güell
Jul 25, 2021·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Miranda MorrisonGeorgios Mantokoudis

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