PMID: 7082438Apr 1, 1982Paper

Use of a countercurrent immunoelectrophoretic method for isolating antistaphylococcal antibodies and staphylococcal antigen in the blood serum of children with staphylococcal infections

Zhurnal mikrobiologii, epidemiologii, i immunobiologii
G A FomenkoI I Babich


In cases of staphylococcal infection in children (osteomyelitis, purulent destructive pneumonia, phlegmons, abscesses) the use of counter immunoelectrophoresis (CIE) allowed one to detect antistaphylococcal antibodies (anti-poly-A beta) in 12.5-69.1% of cases and staphylococcal antigen in the blood serum in 6.1-25.0% of cases, the antigen titer reaching 1 : 1-1 :8. In staphylococcal sepsis with faintly pronounced local pyo-inflammatory processes, as well as in diseases of nonstaphylococcal etiology and in healthy children, no clear reactions indicating the presence of antistaphylococcal antibodies and staphylococcal antigen were registered. CIE may be used as a specific serological diagnostic test in the severe forms of staphylococcal infection in children.

Related Concepts

Antibodies, Bacterial
Antigens, Bacterial
Countercurrent Electrophoresis Measurement
Staphylococcal Infections
Staphylococcus aureus
Teichoic Acids

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