Use of a Cybex NORM dynamometer to assess muscle function in patients with thoracic cancer.

BMC Palliative Care
Andrew WilcockSimon Mockett

Abstract

The cachexia-anorexia syndrome impacts on patients' physical independence and quality of life. New treatments are required and need to be evaluated using acceptable and reliable outcome measures, e.g. the assessment of muscle function. The aims of this study were to: (i) examine the acceptability and reliability of the Cybex NORM dynamometer to assess muscle function in people with non-small cell lung cancer or mesothelioma; (ii) compare muscle function in this group with healthy volunteers and; (iii) explore changes in muscle function over one month. The test consisted of 25 repetitions of isokinetic knee flexion and extension at maximal effort while seated on a Cybex NORM dynamometer. Strength and endurance for the quadriceps and hamstrings were assessed as peak torque and total work and an endurance ratio respectively. Thirteen patients and 26 volunteers completed the test on three separate visits. Acceptability was assessed by questionnaire, reliability by intraclass correlation coefficients (ICC) and tests of difference compared outcomes between and within groups. All subjects found the test acceptable. Peak torque and work done were reliable measures (ICC >0.80), but the endurance ratio was not. Muscle function did not di...Continue Reading

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Citations

Apr 25, 2012·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Chueh-Lung HwangYing-Tai Wu
Dec 18, 2013·Seminars in Oncology·Michael D StubblefieldKirsten K Ness
Apr 9, 2011·Journal of Cachexia, Sarcopenia and Muscle·Robert D KilgourJosé A Morais
Jul 28, 2016·Clinical Lung Cancer·Andrew J MurtonAndrew Wilcock
Nov 30, 2016·Journal of Cachexia, Sarcopenia and Muscle·Oliver KlassenJoachim Wiskemann
Jan 22, 2021·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Gohar AzharRobert R Wolfe

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Methods Mentioned

BETA
surgical resection

Software Mentioned

Statistical Package for the Social Sciences ( SPSS )

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