Use of a dual lumen port for automated red cell exchange in adults with sickle cell disease

Journal of Clinical Apheresis
Anuj ShresthaJoshua J Field

Abstract

Red cell exchange (RCE) is a common procedure in adults with sickle cell disease (SCD). Implantable dual lumen Vortex (DLV) ports can be used for RCE in patients with poor peripheral venous access. We performed a retrospective cohort study of RCE procedures performed in adults with SCD. The main objective of the study was to compare the inlet speed, duration of procedures and rate of complications performed through DLV ports to those performed through temporary central venous and peripheral catheters. Twenty-nine adults with SCD underwent a total of 318 RCE procedures. Twenty adults had DLV ports placed and 218 procedures were performed using DLV ports. Mean length of follow-up after DLV port placement was 397 ± 263 days. Six DLV ports were removed due to infection and 1 for malfunction after a mean of 171 ± 120 days. Compared to temporary central venous and peripheral catheters, DLV port procedures had a greater rate of procedural complications, a longer duration, and a lower inlet speed (all P < 0.01). When accounting for the maximum allowable inlet speed to avoid citrate toxicity, 40% of DLV port procedures were greater than 10% below maximum speed, compared to 7 and 14% of procedures performed through temporary central veno...Continue Reading

Citations

Jun 21, 2016·Journal of Clinical Apheresis
Sep 16, 2016·Journal of Clinical Apheresis·Daniel PutensenJasmin Rivera
Nov 5, 2016·American Journal of Hematology·Marianne DelvilleJustine Gellen-Dautremer
Feb 22, 2017·Frontiers in Pediatrics·Richard H Ko, Courtney D Thornburg
Jul 4, 2019·Journal of Clinical Apheresis·Yvette C TanhehcoGay Wehrli
Feb 15, 2018·Transfusion·David Ming-Hung Lin, Yanyun Wu
Dec 15, 2018·Journal of Clinical Apheresis·Lance A WilliamsMarisa B Marques
Feb 15, 2018·Transfusion·Anand Padmanabhan
Nov 6, 2018·Journal of Clinical Apheresis·Shaun LawickiQuentin Eichbaum
Feb 15, 2018·Transfusion·Jeffrey SzymanskiGeorge Despotis

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