Use of a generic violet light in the surgical management of medication-related osteonecrosis of the jaws: a technical note

Oral and Maxillofacial Surgery
Caroline BallardinGlaykon Alex Vitti Stabile

Abstract

Fluorescence-guided surgery has been recommended for the diagnosis of bone margins in cases of mandibular osteonecrosis. In this article, we report a case in which a generic violet light was used in order to activate bone fluorescence after the administration of tetracycline derivatives, as an alternative to a specific, more expensive equipment that is commercially available for this purpose. The patient had been using alendronate for osteoporosis, resulting in medication-related osteonecrosis of the jaws. The treatment protocol includes preoperative administration of doxycycline and the application of a generic violet light during surgery in order to observe the fluorescence of bone in response to excitation through the light emitted by this device. With an effective visualization of the limit between healthy and devitalized bone tissue, it was possible to perform the necrotic tissue removal. The lesion regressed from stage 2 to stage 0, with no clinical or radiographic evidence of necrotic bone. These results suggest the feasibility of using a generic violet light source as a low-cost alternative for fluorescence-guided surgery.

References

Feb 1, 1980·The Anatomical Record·A Vignery, R Baron
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Jun 1, 2004·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Bryan R HarveyRobert J Defalco
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Sep 2, 2014·Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology·Gianluca PorcaroFabrizio Carini
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