Use of a mixture of surrogates for infectious bioagents in a standard approach to assessing disinfection of environmental surfaces.

Applied and Environmental Microbiology
Safaa SabbahS A Sattar

Abstract

We used a mixture of surrogates (Acinetobacter baumannii, Mycobacterium terrae, hepatitis A virus, and spores of Geobacillus stearothermophilus) for bioagents in a standardized approach to test environmental surface disinfectants. Each carrier containing 10 microl of mixture received 50 microl of a test chemical or saline at 22 +/- 2 degrees C. Disinfectant efficacy criteria were > or = 6 log(10) reduction for the bacteria and the spores and > or = 3 log(10) reduction for the virus. Peracetic acid (1,000 ppm) was effective in 5 min against the two bacteria and the spores but not against the virus. Chlorine dioxide (CD; 500 and 1,000 ppm) and domestic bleach (DB; 2,500, 3,500, and 5,000 ppm) were effective in 5 min, except for sporicidal activity, which needed 20 min of contact with either 1,000 ppm of CD or the two higher concentrations of DB.

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Citations

Sep 17, 2011·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Jason E StoutGary M Cox
Mar 13, 2012·International Journal of Environmental Research and Public Health·James HudsonSelvarani Vimalanathan
Aug 14, 2012·Biotechnology and Bioengineering·Yanyan Zhang, Zhiqiang Hu
Jul 9, 2009·BMC Infectious Diseases·Thomas MagulskiJochen Steinmann
Nov 25, 2014·Food and Environmental Virology·Allison VimontJulie Jean
Apr 10, 2013·Expert Review of Anti-infective Therapy·Jason M PogueKeith S Kaye
May 4, 2021·Zoonoses and Public Health·Andrew D WalesRobert H Davies

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