Use of a novel extended blink test to evaluate the performance of two polyvinylpyrrolidone-containing, silicone hydrogel contact lenses

Clinical Ophthalmology
Jeffery SchaferJoseph Chinn

Abstract

Sustained digital display viewing reduces eye blink frequency and tear film stability. To retain water and preserve a smooth optical surface, contact lens manufacturers have integrated the humectant polyvinylpyrrolidone (PVP) into silicone hydrogel contact lenses. In this study, extended blink time (EBT) was used to assess visual stability over a prolonged blink interval of two PVP-containing silicone hydrogel lenses, samfilcon A (SAM) and senofilcon A (SEN). This randomized, bilateral, masked, crossover study assessed lens performance in ten subjects after 16 hours of wear. EBT, ie, the time elapsed between cessation of blinking and blur-out of a threshold letter on the acuity chart, was measured. At the end of the wear period, subjects reported duration of computer use and rated visual quality (VQ) and comfort while wearing the assigned lens, and the investigator evaluated lens surface wetting characteristics. Each lens was removed and immediately weighed to determine total water content. EBTs were 10.42 seconds for SAM and 8.04 seconds for SEN (p = 0.015). Subjective ratings of VQ after 16 hours of wear were 84.6 for SAM and 74.4 for SEN (p = 0.049). Comfort ratings were 85.9 for SAM and 80.2 for SEN (p > 0.05). Median times...Continue Reading

Citations

Oct 31, 2020·Clinical Ophthalmology·William ReindelRobert Steffen
Oct 29, 2020·Contact Lens & Anterior Eye : the Journal of the British Contact Lens Association·Erol Havuz, Onur Gokmen
Mar 30, 2021·Contact Lens & Anterior Eye : the Journal of the British Contact Lens Association·Mark WillcoxLyndon Jones
Mar 30, 2021·Contact Lens & Anterior Eye : the Journal of the British Contact Lens Association·Fiona StapletonJames S Wolffsohn

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