PMID: 2107141Feb 1, 1990Paper

Use of a quality assurance scheme in a long-term multicentric study of antibiotic susceptibility of Neisseria gonorrhoeae

Genitourinary Medicine
J W Tapsall

Abstract

Experience with a quality control programme for a multicentric collaborative study of antibiotic susceptibility of Neisseria gonorrhoeae is described. The Australian Gonococcal Surveillance Programme (AGSP) has monitored the antibiotic sensitivity of gonococci by surveying results of quantitative sensitivity tests performed in a number of centres throughout the country since 1981. A standardised system of testing by means of agar plate dilution was adopted to ensure uniformity of methods and results and to permit temporal and regional differences in antibiotic sensitivity to be identified and compared. A control programme was developed to provide quality assurance regarding each laboratory's performance. Over a period of nine years more than 3600 MIC determinations on control strains, examined as unknowns, were performed. An overall error rate of 3.1% was observed. Higher error rates were noted in the beginning of the programme but these declined as the study progressed. In addition repeat and duplicate testing of strains was performed. The results of these tests also indicated an improvement in performance over the study period. Close attention to all aspects of the testing procedure reduced the number of errors recorded. At t...Continue Reading

Citations

Oct 12, 2012·Cardiovascular Psychiatry and Neurology·Ioannis HeliopoulosGeorgios Tsivgoulis
Oct 3, 2018·Journal of Pediatric Neurosciences·Manoj SingrakhiaAjit Jangle
Mar 3, 2020·Communicable Diseases Intelligence·Monica M LahraC R Robert George
Jul 16, 2020·Communicable Diseases Intelligence·Monica M LahraUNKNOWN National Neisseria Network, Australia
May 4, 2021·Communicable Diseases Intelligence·Monica M LahraBenjamin H Armstrong

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