PMID: 9419094Jan 7, 1998Paper

Use of a screening RAST in a large neuro-otologic practice

Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery
B K HowardC S Mabry

Abstract

Evidence in the literature emphasizes the role of the immune system in disorders of the inner ear and eustachian tube. We initially investigated the presence of inhalant allergy in selected patients seen for otologic problems by means of a screening radioallergosorbent test (RAST), using either a microscreen or a limited antigen panel. This study analyzed the results of tests performed over a 2-year period on 186 patients seen by one of us (WLM) for treatment of vertigo (66%), tinnitus (63%), hearing loss (49%), aural fullness (48%), Meniere's quadrad (27%), balance disturbance other than true vertigo (21%), and eustachian tube dysfunction (4%). We found an incidence of immunoglobulin E-mediated hypersensitivity of nearly 40% in a patient population selected solely for neuro-otologic symptoms and not for sinonasal symptoms. This figure is more than double that quoted for the general population. We also found a surprisingly high incidence of mold antigen atopy in this selected population. Allergy can contribute to a number of otologic symptoms, including eustachian tube dysfunction, vertigo, tinnitus, hearing loss, aural fullness, and nonspecific balance disturbance. Allergy also has been emphasized as an etiologic factor in a p...Continue Reading

References

May 1, 1983·The Journal of Allergy and Clinical Immunology·R A FriedmanP Fireman
Jul 1, 1997·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·A J LehrC S Mabry

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Citations

Sep 29, 2007·Advances in Therapy·Bülent TopuzCüneyt Orhan Kara
Apr 29, 2008·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Sang Duk HongKyu-Whan Chung
Jan 28, 2004·Otolaryngologic Clinics of North America·John H KrouseAnand Shah
Mar 31, 2000·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·P Sabini, A P Sclafani
Jan 28, 2004·Otolaryngologic Clinics of North America·Richard L Mabry
Mar 11, 2008·Otolaryngologic Clinics of North America·Richard C Haydon

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