Use of a web-based app to improve breast cancer symptom management and adherence for aromatase inhibitors: a randomized controlled feasibility trial

Journal of Cancer Survivorship : Research and Practice
Ilana GraetzLee S Schwartzberg

Abstract

For postmenopausal women with hormone receptor-positive breast cancer, long-term use of aromatase inhibitors (AIs) significantly reduces the risk of cancer recurrence and improves survival. Still, many patients are nonadherent due to adverse side effects. We conducted a pilot randomized controlled trial to test the use of a web-based application (app) designed with and without weekly reminders for patients to report real-time symptoms and AI use outside of clinic visits with built-in alerts to patients' oncology providers. Our goal was to improve symptom burden and medication adherence. Forty-four women with early-stage breast cancer and a new AI prescription were randomized to either an App+Reminder (weekly reminders to use app) or an App (no reminders) group. Pre- and post-assessment data were collected from all participants. Participants in the App+Reminder group had higher weekly app usage rate (74 vs. 38%, p < 0.05) during the intervention and reported higher AI adherence at 8 weeks (100 vs. 72%, p < 0.05). Symptom burden increase was higher for the App group compared to the App+Reminder group but did not reach statistical significance. Weekly reminders to use a web-based app to report AI adherence and treatment-related sy...Continue Reading

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Citations

Aug 29, 2019·JMIR MHealth and UHealth·Flávia Oliveira Almeida Marques CruzPaula Elaine Diniz Dos Reis
Sep 7, 2019·European Journal of Gastroenterology & Hepatology·Changqing ZhaoMindie H Nguyen
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Oct 6, 2020·Curēus·Bradley A McGregorAndrew E Hendifar
Aug 28, 2020·Health Informatics Journal·Akshat KapoorElizabeth Baker
Jul 14, 2021·JMIR Formative Research·Cynthia F CorbettJason M O'Kane
Jul 9, 2021·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Zoe MoonLyndsay D Hughes
Jul 17, 2021·Clinical Journal of Oncology Nursing·Naomi Cazeau

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