Use of an acellular regenerative tissue matrix in combination with vacuum-assisted closure therapy for treatment of a diabetic foot wound

The Journal of Foot and Ankle Surgery : Official Publication of the American College of Foot and Ankle Surgeons
Kyle L RandallRichard T Laughlin

Abstract

Diabetic foot ulcers can be difficult to treat for a variety of reasons, and may result in amputation. The use of skin grafts can often be a useful method of achieving wound coverage and subsequent healing of diabetic foot ulcers; however, this method of treatment requires creation of a donor site wound that adds to the patient's overall wound burden. Application of an acellular regenerative tissue matrix may eliminate the need for harvesting a skin graft in order to cover a nonhealing wound. The use of vacuum-assisted wound closure has been shown to promote an environment that enhances wound bed contraction and surface epithelialization. The combination of an acellular regenerative tissue matrix with vacuum-assisted wound closure can be used to promote healing in the management of a nonhealing diabetic foot wound. x.

Citations

Sep 26, 2009·Clinics in Podiatric Medicine and Surgery·Thomas M Rocchio
Jul 9, 2010·Foot & Ankle Specialist·Claire M CapobiancoThomas Zgonis
Nov 5, 2019·The International Journal of Lower Extremity Wounds·Davide MelandriElena Bondioli

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