PMID: 590836Oct 1, 1977

Use of an elemental diet (Vivonex) in the management of bile acid-induced diarrhoea

L M NelsonS O Atherton


The effect of a low fat containing elemental diet (Vivonex) on faecal bile acid excretion was studied in six patients with cholerheic diarrhoea, two normal controls, and four patients with non-cholerheic diarrhoea. The total faecal bile acid excretion for the patients with bile acid-induced diarrhoea was significantly reduced fron 6-37+/- 1-64 mmol/24 h (mean +/- SEM) to 2-70 +/- 1-12 mmol/24 h during Vivonex treatment (p less than 0-05). A marked improvement in the diarrhoea of these patients occurred; the number of stools per day decreased and there was less urgency associated with the diarrhoea. No significant reduction in faecal bile acid excretion was observed for the control and non-cholerheic diarrhoea groups. An elemental diet of this type may be of value in the management of patients with bile acid-induced diarrhoea unresponsive to other forms of therapy, and may be of particular value in patients with Crohn's disease.


Jan 1, 1975·Gut·R I Russel
Oct 1, 1972·Archives of Internal Medicine·A F Hofmann
Dec 1, 1972·The American Journal of Clinical Nutrition·H R AtteberyS M Finegold
Aug 21, 1969·The New England Journal of Medicine·A F Hofmann, J R Poley
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Feb 1, 1980·Digestive Diseases and Sciences·C L MorinD Bourassa
Feb 1, 1997·Alimentary Pharmacology & Therapeutics·T S KingJ O Hunter
May 1, 1978·The Proceedings of the Nutrition Society·R I Russell
Feb 1, 1985·The Proceedings of the Nutrition Society·R I Russell
Jan 1, 1983·Nutrition and Cancer·D M KlurfeldD Kritchevsky
May 1, 1982·JPEN. Journal of Parenteral and Enteral Nutrition·C L MorinN Lapointe
Jul 1, 1986·JPEN. Journal of Parenteral and Enteral Nutrition·L M Nelson, R I Russell
Mar 26, 2010·Scandinavian Journal of Gastroenterology·Antal BajorHasse Abrahamsson
Jan 1, 1982·Critical Reviews in Microbiology·S D Chaparas
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Oct 5, 2017·Clinical Medicine : Journal of the Royal College of Physicians of London·Amy JacksonH Jervoise N Andreyev
Oct 1, 1979·Scottish Medical Journal·R I Russell, M J Hall
Jun 1, 1991·Alimentary Pharmacology & Therapeutics·R I Russell
Sep 1, 1986·Scandinavian Journal of Gastroenterology·I BosaeusH Andersson
Jun 1, 1988·International Journal of Colorectal Disease·T Barton, M R Lewin
Apr 1, 1978·Scottish Medical Journal·S O Atherton, R I Russell
Mar 29, 2018·International Journal of Colorectal Disease·Jonathan YdeHanne B Moeller
Dec 16, 1978·The Medical Journal of Australia·R B SewellR A Smallwood

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