PMID: 9432077Jan 31, 1998Paper

Use of antibiotic prophylaxis in ear surgery

The Laryngoscope
P J GovaertsF E Offeciers

Abstract

A prospective, double-blind, randomized, placebo-controlled study was performed to evaluate the effect of antibiotic prophylaxis in ear surgery. The present study reports on the results of 750 patients, half of whom received cefuroxime for 1 day, the other half, placebo. All postoperative infections occurring within 2 weeks after the intervention were recorded, together with several preoperative and perioperative parameters. It is concluded that exploratory tympanoplasties (including stapedotomy) and "dry perforation" tympanoplasties should be considered "clean" operations according to the American National Research Council and do not benefit from antibiotic prophylaxis. On the other hand, tympanoplasties performed on draining ears and on ears with cholesteatoma should be considered "dirty" operations for which antibiotic prophylaxis may decrease the postoperative infection rate by factor 3. All postoperative infections healed without sequels under proper treatment, except for three that resulted in graft necrosis--one in the placebo group and two in the cefuroxime group. In consequence, prophylaxis may not be mandatory in the dirty group, although the authors advocate its use for the sake of patient and surgeon comfort.

References

Oct 1, 1988·The Laryngoscope·C G Jackson
Dec 1, 1972·Acta Oto-laryngologica·J MarquetK J Van Camp
Dec 1, 1994·The Annals of Otology, Rhinology, and Laryngology·T SomersE Offeciers
Jan 1, 1993·Archives of Surgery·C P PageD H Wittmann
Nov 1, 1996·The Annals of Otology, Rhinology, and Laryngology·E P HamansF E Offeciers

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Citations

May 17, 2012·The Laryngoscope·Sachin GuptaAnil K Lalwani
May 17, 2008·Annales d'oto-laryngologie et de chirurgie cervico faciale : bulletin de la Société d'oto-laryngologie des hôpitaux de Paris·M BertrandJ-P Marie
Jan 12, 2010·Acta otorrinolaringológica española·Sergio ObesoCarlos Suárez
Dec 18, 2013·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Ilker Burak ArslanIbrahim Cukurova
Aug 9, 2016·The Laryngoscope·Nathan E Pierce, Patrick J Antonelli
Sep 19, 2012·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Adrian L James, Blake C Papsin
Feb 7, 2018·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Priyesh N PatelDavid O Francis
Jun 10, 2005·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·James C LeePatrick J Antonelli
Sep 7, 2005·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Erol KeleşYavuz Selim Demir
Jul 22, 2004·The Cochrane Database of Systematic Reviews·H P VerschuurP P G van Benthem
Apr 3, 2019·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Zaid Al-QurayshiEmad Kandil
Feb 9, 2000·The Journal of Laryngology and Otology·P J Dawes
May 20, 2020·World Journal of Otorhinolaryngology - Head and Neck Surgery·Yuan F LiuTimothy T Jung

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