Use of aripiprazole in clozapine induced enuresis: report of two cases.

Journal of Korean Medical Science
Myung-Ji Lee, Chul-Eung Kim

Abstract

This report describes the efficacy of combined use of aripiprazole in the treatment of a patient with clozapine induced enuresis. Aripiprazole acts as a potential dopamine partial agonist and the dopamine blockade in the basal ganglia might be one of the causes of urinary incontinence and enuresis. We speculate that aripiprazole functioned as a D2 agonist in hypodopaminergic state of basal ganglia caused by clozapine and maintained dopamine level that would improve enuresis ultimately.

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Citations

Apr 1, 2013·Acta Neuropsychiatrica·Enrica Di RosaGiampaolo Perna
Jun 10, 2011·The British Journal of Psychiatry : the Journal of Mental Science·Mira Harrison-WoolrychDavid C G Skegg
Jan 5, 2012·The British Journal of Psychiatry : the Journal of Mental Science·Thomas R E BarnesCarol Paton
Nov 26, 2015·Indian Journal of Pharmacology·Pradeep Palaniappan
Apr 30, 2015·The Australian and New Zealand Journal of Psychiatry·Navin Dadlani, Marni Austin
Nov 29, 2016·Journal of Child and Adolescent Psychopharmacology·Saliha KılınçSabri Hergüner
Jun 17, 2020·Clinical Neuropharmacology·Serdar Karatoprak, Necati Uzun
Oct 4, 2020·Journal of Clinical Psychopharmacology·Sowmya SelvarajGanesan Venkatasubramanian
Apr 23, 2021·Journal of Medical Case Reports·Rosaria NardelloSalvatore Mangano
Aug 16, 2021·Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie·Amin ArastehSeyede Saba Mostafavi Montazeri

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