Use of bacterial lipopolysaccharide (LPS) as an immunostimulant for the control of Aeromonas hydrophila infections in rainbow trout Oncorhynchus mykiss (Walbaum)

Journal of Applied Microbiology
E J Nya, B Austin

Abstract

To determine the effect of lipopolysaccharide (LPS) for the prevention of infection by Aeromonas hydrophila in rainbow trout (Oncorhynchus mykiss Walbaum) fingerlings. Rainbow trout fingerlings were fed with 0 mg (= controls), 1.875 mg, 3.75 mg, 7.5 mg and 15 mg of LPS per 100 g of commercial feed for 14 days before experimental challenge with A. hydrophila. The results revealed a reduction in mortalities to 5% in the two lowest doses and 15% in the group, which received 15 mg LPS per 100 g of feed, compared with 45% mortalities in the control. LPS exerted a powerful oxidative burst effect and was a potent mediator of phagocytic, lysozyme, bactericidal and antiprotease activities and total protein. However, whereas there were increases in specific growth rate (SGR), feed conversion ratio (FCR) and protein efficiency ratio (PER) in LPS-treated fish, the data were not significantly (P > 0.05) different. LPS was effective at preventing disease caused by A. hydrophila and in stimulating the innate immune response of rainbow trout. The results of this study highlight the role of LPS in fish disease control.

References

Apr 1, 1977·Infection and Immunity·P H QuinnE R Moxon
Aug 1, 1989·Archives of Internal Medicine·J Eastaugh, S Shepherd
Jan 1, 1988·Journal of Cell Science. Supplement·R A Ezekowitz, P D Stahl
Jan 1, 1987·Annual Review of Medicine·D C Morrison, J L Ryan
Jan 1, 1985·Developmental and Comparative Immunology·L W ClemN W Miller
Apr 1, 1995·Clinical Microbiology Reviews·J C Hurley
Jan 1, 1993·Advances in Immunology·R J Ulevitch
Nov 1, 1993·Proceedings of the National Academy of Sciences of the United States of America·P GallayM P Glauser
Mar 1, 1994·Proceedings of the National Academy of Sciences of the United States of America·D W DunneK A Joiner
Mar 22, 1996·Proceedings. Biological Sciences·A WhiteR G Bowers
Nov 1, 1996·Developmental and Comparative Immunology·G F WiegertjesW B van Muiswinkel
Feb 3, 2000·Journal of Biotechnology·D Petsch, F B Anspach
Sep 12, 2000·Developmental and Comparative Immunology·M R SarderB J McAndrew
Jun 26, 2001·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Z BircanA Vitrinel
Jun 26, 2001·Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology·K K SørensenB Smedsrød
Oct 17, 2001·Developmental and Comparative Immunology·A E Ellis
Oct 23, 2002·ILAR Journal·Michael F W Festing, Douglas G Altman
Nov 27, 2002·Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences·Chuichi Hirayama, Masayo Sakata
Jun 12, 2003·Developmental and Comparative Immunology·James L StaffordBrad G Magor
Aug 28, 2003·Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology·Sigrun Lange, Bergljót Magnadóttir
Apr 12, 2005·Fish & Shellfish Immunology·Dharitri ChoudhuryS C Mukherjee
Jun 14, 2005·Fish & Shellfish Immunology·H BoshraJ O Sunyer
Jun 21, 2007·Diseases of Aquatic Organisms·Oivind Bergh
Feb 22, 2008·Fish & Shellfish Immunology·S K NayakN K Maiti

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Citations

Jun 12, 2013·Developmental and Comparative Immunology·Wanilada RungrassameePikul Jiravanichpaisal
Jul 6, 2014·Environmental Science and Pollution Research International·S JollyS Betoulle
Mar 19, 2011·Developmental and Comparative Immunology·Aja M Rieger, Daniel R Barreda
Mar 8, 2011·Fish & Shellfish Immunology·Luca TacchiSamuel A M Martin
Apr 16, 2016·Fish & Shellfish Immunology·Sib Sankar GiriSe Chang Park
Jun 14, 2016·International Journal of Food Microbiology·Oluwafemi Ayodeji AdeboVuyo Mavumengwana
Nov 3, 2010·Qualitative Health Research·Eileen J PorterSandy Matsuda
Dec 12, 2012·New Directions for Child and Adolescent Development·Laura Ferrer-WrederShahram Mansoory
Mar 17, 2020·Biocontrol Science·Chun Yao AngTamrin M Lal
Jul 10, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Klaudia KowalikMichał Tomczyk
Jan 24, 2017·EFSA Journal·UNKNOWN EMA Committee for Medicinal Products for Veterinary Use (CVMP) and EFSA Panel on Biological Hazards (BIOHAZ)Helen Jukes

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