Use of Berlin questionnaire in comparison to polysomnography and home sleep study in patients with obstructive sleep apnea

Respiratory Research
Susanna S S NgDavid S C Hui

Abstract

Obstructive sleep apnea syndrome (OSAS) is a common disorder with significant morbidity and mortality. We aimed to evaluate the predictive accuracy of the Berlin questionnaire in patients with suspected OSAS undergoing PSG in the sleep laboratory setting against those going through the Embletta™ portable diagnostic system (Embletta PDS) at home. Patients with suspected OSAS were recruited from respiratory clinics to complete Berlin questionnaire and Epworth Sleepiness Score (ESS). Patients were randomized to undergo either home-based sleep test (group A) or hospital-based polysomnography (PSG) (group B). Three hundreds and sixteen subjects with newly referred suspected OSAS were recruited and randomized into group A (n = 157) and group B (n = 159). The prevalence of moderate to severe OSAS defined as apnea-hypopnea index (AHI) ≥ 15/h was 54%. The Berlin questionnaire identified 69.7% (n = 99) of subjects as high risk in group A and 77.5% (n = 100) in group B. The sensitivity, specificity, negative predictive value (NPV), and positive predictive value (PPV) of the questionnaire to predict an AHI ≥ 15/h as diagnosed by PSG was 78, 23, 67 and 35%. When compared with Embletta PDS, the specificity and NPV increased to 48 and 63%. Th...Continue Reading

Associated Clinical Trials

Apr 10, 2013·Prof David Shu Cheong Hui, Prof David Shu Cheong Hui

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Citations

Apr 30, 2021·Journal of Sleep Research·Masoud TahmasianMojtaba Zarei

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Clinical Trials Mentioned

NCT01828216

Software Mentioned

Statistical Package of the Social Science ( SPSS )
PDS
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