PMID: 9209793Jun 1, 1997Paper

Use of cardiac markers as assessed by outcomes analysis

Clinical Biochemistry
A H Wu

Abstract

This article will describe the outcomes studies that have been performed or are needed in relation to biochemical markers in coronary artery diseases (CAD). Studies in five major areas are reviewed: the need for emergency department (ED) chest pain centers and the role of cardiac markers; impact of cardiac marker testing frequency on length of stay (LOS); interpretation of cardiac troponins T and I for risk stratification of cardiac patients with unstable angina (UA); serum markers for determining the success of intravenous thrombolytic therapy following acute myocardial infarction (AMI), and its role in rescue percutaneous transluminal coronary angioplasty (PTCA); and need and criteria for implementation of new cardiac tests. Chest pain centers reduce unnecessary admissions and costs for AMI rule outs. Laboratories must perform testing on a stat basis for rapid rule out of AMI. Stat testing will also result in a reduction in hospital LOS for patients who rule in for AMI. For UA patients, studies are needed to determine how results of cardiac markers can be used to improve cardiac outcomes. Serial measurements of myoglobin offer the earliest discrimination for successful reperfusion, and should be used if rescue PTCA becomes im...Continue Reading

References

Apr 1, 1978·The Journal of Clinical Investigation·S F VatnerP R Maroko
Dec 10, 1992·The New England Journal of Medicine·P O Collinson, P J Stubbs
Jan 1, 1992·Clinical and Experimental Hypertension. Part A, Theory and Practice·J H Laragh
Jan 30, 1992·The New England Journal of Medicine·V FusterJ H Chesebro
Jul 15, 1991·The American Journal of Cardiology·J M GaspozL Goldman
Jan 1, 1986·Medical Decision Making : an International Journal of the Society for Medical Decision Making·W M TierneyF K Anderson
Nov 1, 1995·The American Journal of Cardiology·A H WuD Waters
Sep 1, 1994·The New England Journal of Medicine·P R PuleoJ L Zimmerman
Aug 18, 1994·The New England Journal of Medicine·G LiuzzoA Maseri
Nov 1, 1994·Journal of the American College of Cardiology·J M GaspozL Goldman
Jul 15, 1994·The American Journal of Cardiology·UNKNOWN CORAMI Study Group (COhort of Rescue Angioplasty in Myocardial Infarction)
Apr 1, 1994·Clinical Biochemistry·A BurlinaF Accorsi
May 1, 1994·Journal of the American College of Cardiology·S AbeK Kiyonaga
Nov 1, 1993·Scandinavian Journal of Clinical and Laboratory Investigation·J RavkildeA Asberg
Dec 16, 1993·The American Journal of Cardiology·P KlootwijkM L Simoons
Mar 1, 1993·Journal of the American College of Cardiology·R L WilenskyJ A Zeller
Jan 1, 1993·International Journal of Cardiology·A E AránegaA Aránega
Mar 28, 1996·The New England Journal of Medicine·M A Testa, D C Simonson

❮ Previous
Next ❯

Citations

Aug 7, 1999·International Journal of Clinical & Laboratory Research·M Plebani, M Zaninotto
Jun 7, 2005·Clinica Chimica Acta; International Journal of Clinical Chemistry·Hong LiuHua Jing
Nov 14, 2000·Clinica Chimica Acta; International Journal of Clinical Chemistry·V RicchiutiF S Apple
Sep 15, 2001·Clinica Chimica Acta; International Journal of Clinical Chemistry·M Panteghini
Nov 14, 2000·Clinical Biochemistry·P St-Louis
Mar 8, 2002·Paediatric Anaesthesia·Onur OzlüAli Mert
Feb 25, 2000·Therapeutic Drug Monitoring·M J McQueen
May 16, 2006·Clinica Chimica Acta; International Journal of Clinical Chemistry·A Dolci, M Panteghini

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cardiovascular Inflammation

Inflammation plays a significant role in the development of cardiovascular diseases, an understanding of these endogenous processes is critical for evaluating the risks and potential treatment strategies. Discover the latest research on cardiovascular inflammation here.

Related Papers

Clinical Chemistry and Laboratory Medicine : CCLM
B Puschendorf
Clinical Chemistry and Laboratory Medicine : CCLM
F PaganiM Panteghini
European Journal of Clinical Chemistry and Clinical Biochemistry : Journal of the Forum of European Clinical Chemistry Societies
M ZaninottoM Plebani
© 2022 Meta ULC. All rights reserved