PMID: 490577Aug 1, 1979Paper

Use of chromosomal translocations with in situ DNA hybridisation to confirm localisation of human 5S ribosomal RNA genes

Journal of Medical Genetics
S J FennellM A Ferguson-Smith

Abstract

Two cases of chromosomal translocations involving the long arm of chromosome 1 were investigated for 5S ribosomal gene localisation using in situ hybridisation. In the first family, there was an interstitial translocation of 1q25-32 to chromosome 5; the 5S genes remained on chromosome 1. In the second family, there was a translocation of 1q42-44 to chromosome 21q12; the 5S gene locus in this case was translocated. This shows that the 5S ribosomal genes are at position 1q42-44, confirming a previous assignment based on adenovirus-induced uncoiling and on a partial trisomy (Steffensen et al., 1977).

References

Jan 1, 1978·Cytogenetics and Cell Genetics·A S HendersonK C Atwood
Jul 1, 1976·Experimental Cell Research·D M SteffensenJ K McDougall
Jan 28, 1976·Human Genetics·A S Henderson, K C Atwood
Jan 1, 1975·Cytogenetics and Cell Genetics·D M SteffensenJ L Hamerton
Jul 20, 1973·Humangenetik·R Czaker
Oct 1, 1974·Experimental Cell Research·T CasperssonK Kvarnström
Jun 1, 1973·Proceedings of the National Academy of Sciences of the United States of America·W PrenskyW L Hughes
Jan 1, 1973·Chromosoma·M L PardueM L Birnstiel
Mar 28, 1971·Journal of Molecular Biology·L Hatlen, G Attardi
May 25, 1971·Biochemistry·S L Commerford
Jun 12, 1970·Science·M L Pardue, J G Gall
Jun 1, 1969·FEBS Letters·B G. Barrell, F Sanger

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Citations

Oct 1, 1986·Annals of Human Genetics·C A Smith
Jan 1, 1985·Biotechnology & Genetic Engineering Reviews·J D BrookA L Meredith
Mar 9, 2019·Reviews in the Neurosciences·Caitlin NyhusVanessa Jane Hall

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