Use of cold atmospheric plasma in the treatment of cancer

Biointerphases
Parker BabingtonJonathan Sherman

Abstract

Cold atmospheric plasma (CAP) is an emerging modality for the treatment of solid tumors. In-vitro experiments have demonstrated that with increasing doses of plasma, tumor cells assays display decreased cell viability. CAP is theorized to induce tumor cells into apoptosis via multiple pathways including reactive oxygen and nitrogen species as well as cell cycle disruption. Studies have shown CAP treatment can decrease mouse model glioblastoma multiforme tumor volume by 56%, increase life span by 60%, and maintain up to 85% viability of normal cells. Emerging evidence suggests that CAP is a viable in-vivo treatment for a number of tumors, including glioblastoma, as it appears to selectively induce tumor cell death while noncancerous cells remain viable.

References

May 13, 1999·Biochimica Et Biophysica Acta·R P PatelV M Darley-Usmar
Jun 28, 2011·International Journal of Cancer. Journal International Du Cancer·Marc VandammeAlain Le Pape
Aug 9, 2011·Biosensors & Bioelectronics·Jae Young KimSung-O Kim
Oct 8, 2011·British Journal of Cancer·M KeidarB Trink
Sep 8, 2012·Scientific Reports·O VolotskovaM Keidar
Jan 22, 2013·Journal of Pediatric Surgery·Ryan M WalkAnthony D Sandler
Oct 3, 2013·Medical Gas Research·Clotilde HoffmannJohn Zhang
Jun 1, 2014·PloS One·Xiaoqian ChengMichael Keidar
Jul 23, 2014·International Journal of Molecular Medicine·Rafael Guerrero-PrestonBarry Trink

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Citations

Jul 22, 2018·Biological Chemistry·Sander BekeschusAnke Schmidt
Nov 7, 2019·Oxidative Medicine and Cellular Longevity·Angela Privat-MaldonadoSander Bekeschus
Jul 27, 2018·Therapeutic Advances in Medical Oncology·Antoine DubucSarah Cousty
Oct 21, 2020·International Journal of Molecular Sciences·Chang-Min LeeByung-Hoon Kim
Mar 4, 2021·Experimental Biology and Medicine·Sung-Tak LeeDae-Seok Hwang
Mar 19, 2021·Molecular Biology Reports·Fernando MendesMaria Filomena Botelho
Apr 4, 2021·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Helena MotalnBoris Rogelj
Jun 22, 2021·Nanomedicine : Nanotechnology, Biology, and Medicine·Sebnem GunesJames F Curtin
Jul 26, 2021·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Zhonglei HeWenxin Wang
Mar 31, 2017··Zulaika AbdullahC. W. S. R. Mohamad

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