PMID: 6972750Jul 1, 1981Paper

Use of cold cardioplegic solution for vein graft distention and preservation: a light and scanning electron microscopic study

The Annals of Thoracic Surgery
M KuruszE H Williams

Abstract

To evaluate the effect of a cardioplegic solution on the endothelium of the saphenous vein, portions of this vein were harvested from each of 5 patients undergoing coronary artery bypass operation. Each sample was divided into five segments. One segment was distended with heparinized saline solution, one with heparinized blood, and one with heparinized cardioplegic solution (25 mEq of potassium per liter). All of the distending solutions were kept at 10 degrees C, and pressure was carefully limited to 200 mm Hg. The fourth segment of vein was distended with heparinized saline solution but no effort was made to limit distending pressure, and the fifth segment was not distended. All samples were then examined with light and scanning electron microscopy. There were no great morphological differences in the endothelium of veins distended to 200 mm Hg with saline solution, blood, or cardioplegic solution. The morphology of these samples compared favorably with the control vein endothelium although scattered areas of endothelial disruption were present in every sample. Veins distended without pressure control showed massive endothelial disruption. The particular solution used to distend the sephenous veins is not as important as limi...Continue Reading

References

Mar 1, 1975·The Journal of Surgical Research·J C StanleyW J Fry
Nov 1, 1976·Vascular Surgery·V ParsonnetC Montefuso
Oct 3, 1974·The American Journal of Cardiology·K K UnniA L Brown
Feb 1, 1967·The British Journal of Surgery·M McCabeG W Taylor

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Citations

Jan 1, 1990·Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie·A R DresdaleN A Silverman
Feb 1, 1987·Journal of Neurosurgery·T M Sundt, T M Sundt
Mar 1, 1992·The Journal of Surgical Research·D DriesR M Nelson
Apr 14, 2016·Interactive Cardiovascular and Thoracic Surgery·Bernhard WinklerThierry Carrel
Sep 24, 2004·Annals of Plastic Surgery·Thanos P KakoulidisWayne K Stadelmann
Mar 25, 2020·Journal of Cardiac Surgery·Nikolaos A PapakonstantinouEfstratios Apostolakis

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