Use of decimal assay for additivity to demonstrate synergy in pair combinations of econazole, nikkomycin Z, and ibuprofen against Candida albicans in vitro.

Antimicrobial Agents and Chemotherapy
V N TariqN E McCain

Abstract

Interactions between six compounds (econazole, miconazole, amphotericin B, nystatin, nikkomycin Z, and ibuprofen) were investigated for their antifungal activities against Candida albicans by using pair combinations in an in vitro decimal assay for additivity based on disk diffusion. Additive interactions were observed between miconazole and econazole, amphotericin B and nystatin, and amphotericin B and ibuprofen, while an antagonistic interaction was observed between econazole and amphotericin B. Synergistic interactions were recorded for the combinations of econazole and ibuprofen, econazole and nikkomycin Z, and ibuprofen and nikkomycin Z.

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Citations

Jan 18, 2014·Fungal Biology·Whitney M HoldenLouise A Rollins-Smith
Jun 30, 2011·Folia Microbiologica·Andreza Urba de QuadrosMarta Chagas Monteiro
Jan 8, 2014·Expert Opinion on Therapeutic Patents·María Victoria CastelliSusana A Zacchino
Nov 1, 2012·European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences·Aijaz AhmadNikhat Manzoor
Apr 10, 2010·Phytomedicine : International Journal of Phytotherapy and Phytopharmacology·K AmberM Nikhat
Jul 17, 2010·Journal of Medical Microbiology·Aijaz AhmadNikhat Manzoor
Apr 11, 2014·Diagnostic Microbiology and Infectious Disease·Ana Cristina AbreuManuel Simões
Feb 24, 2012·The Brazilian Journal of Infectious Diseases : an Official Publication of the Brazilian Society of Infectious Diseases·Liliane Alves ScheidSydney Hartz Alves
Feb 25, 2015·European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences·Jelena ObadBlaženka Kos
Jan 10, 2018·Antimicrobial Agents and Chemotherapy·Parth N ShahCarolyn L Cannon
Feb 1, 2017·Antimicrobial Agents and Chemotherapy·Petra Zimmermann, Nigel Curtis
May 29, 1999·Antimicrobial Agents and Chemotherapy·R K Li, M G Rinaldi

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