PMID: 698660Sep 2, 1978Paper

Use of digitalis in general practice. Liverpool Therapeutics Group

British Medical Journal

Abstract

A study, which arose out of a general-practitioner teaching programme in clinical pharmacology, was designed to assess the use of digitalis in 391 patients in general practice. Clinical, biochemical, and pharmacological data were used to assess whether digitalis treatment should be discontinued (89 patients; 22.8%); the dose kept unchanged (47; 12%); or the dose increased (47; 12%) or decreased (24; 6.1%). Serum concentrations of cardiac glycoside were below a defined therapeutic range in 159 patients (40.7%), above this range in 37 (9.7%), and within the range in 195 (49.3%). Studies of this kind may help to promote a more critical attitude to prescribing widely used drugs such as digitalis.

References

Nov 19, 1977·Lancet·S M Hull, A Mackintosh
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Citations

Jan 1, 1985·European Journal of Clinical Pharmacology·O Impivaara, E Iisalo
Feb 1, 1980·Irish Journal of Medical Science·G D Johnson, D G McDevitt
Mar 25, 1982·The New England Journal of Medicine·D C LeeE Haber
Jan 1, 1983·Current Medical Research and Opinion·A J Taggart, D G McDevitt
Jul 1, 1986·Journal of the American Geriatrics Society·D D SchockenP P Barry
Aug 16, 1985·Klinische Wochenschrift·M MiddekeH Holzgreve
Feb 8, 1989·The Journal of Pharmacy Technology : JPT : Official Publication of the Association of Pharmacy Technicians·F PucinoC L Beck
Nov 1, 1979·Journal of Clinical Pharmacology·R Spector
Mar 1, 1989·British Journal of Clinical Pharmacology·L NolanK O'Malley
Mar 1, 1982·Journal of the American Geriatrics Society·B M Stults

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