Use of ERC-1671 Vaccine in a Patient with Recurrent Glioblastoma Multiforme after Progression during Bevacizumab Therapy: First Published Report

The Permanente Journal
Daniela A BotaApostolos Stathopoulos

Abstract

Glioblastoma multiforme is a highy aggressive tumor that recurs despite resection, focal beam radiation, and temozolamide chemotherapy. ERC-1671 is an experimental treatment strategy that uses the patient's own immune system to attack the tumor cells. The authors report preliminary data on the first human administration of ERC-1671 vaccination under a single-patient, compassionate-use protocol. The patient survived for ten months after the vaccine administration without any other adjuvant therapy and died of complications related to his previous chemotherapies.

Citations

Aug 29, 2018·International Journal of Molecular Sciences·Virgil E J C SchijnsApostolos Stathopoulos
Oct 3, 2018·Frontiers in Pharmacology·Edouard Alphandéry
Dec 20, 2018·International Journal of Molecular Sciences·Thomas C ChenAxel H Schönthal

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