Use of fibers in childhood constipation treatment: systematic review with meta-analysis

Jornal de pediatria
Patricia Piccoli de MelloElza Daniel de Mello

Abstract

To gather current evidence on the use of fiber for constipation treatment in pediatric patients. Systematic review with meta-analysis of studies identified through Pubmed, Embase, LILACS and Cochrane databases published up to 2016. Randomized controlled trials; patients aged between 1 and 18 years and diagnosed with functional constipation receiving or not drug treatment for constipation; articles published in Portuguese, English, Spanish, French, and German in journals accessible to the researchers. A total of 2963 articles were retrieved during the search and, after adequate evaluation, nine articles were considered relevant to the study objective. A total of 680 children were included, of whom 45% were boys. No statistical significance was observed for bowel movement frequency, stool consistency, therapeutic success, fecal incontinence, and abdominal pain with fiber intake in patients with childhood constipation. These results should be interpreted with care due to the high clinical heterogeneity between the studies and the methodological limitation of the articles selected for analysis. There is a scarcity of qualified studies to evaluate fiber supplementation in the treatment of childhood constipation, generating a low deg...Continue Reading

Citations

Apr 27, 2019·Current Gastroenterology Reports·M J van MillM A Benninga
Feb 27, 2020·Expert Review of Gastroenterology & Hepatology·Bridget R Southwell
Oct 16, 2019·Journal of Medicinal Food·Hannah ParuzynskiJoanne Slavin
Mar 12, 2020·Archives of Disease in Childhood·David TappinJon Heron
Jul 31, 2019·Current Opinion in Obstetrics & Gynecology·Alla Vash-Margita, Marsha K Guess
Nov 17, 2020·Journal of Paediatrics and Child Health·Rishi BoliaMark R Oliver
Feb 4, 2021·Journal of Pediatric Gastroenterology and Nutrition·Shaman RajindrajithMarc Alexander Benninga

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