[Use of fluorides for caries prevention].

Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz
Ulrich Schiffner

Abstract

For a few decades, a decrease in the caries burden in all age groups has been observed in Germany. The regular use of fluoride preparations is described as the main reason for the caries decline. It is well established that topical fluoride application directly to the tooth surfaces in the oral cavity, in particular fluoride-containing toothpastes and fluoride varnishes, is responsible for the decline. Several mechanisms of action, such as the formation of a calcium fluoride layer, remineralization, and the effects on bacterial plaque, were determined to be responsible for the overall clinical effect. All these mechanisms can be effective on enamel and root dentin in patients of all ages. There is a dose-response relationship between the fluoride concentration in the applied preparations and the average caries reduction achieved.There are no general toxicological concerns about topical fluoride application. Fluoride toothpastes should be used from the eruption of the first deciduous tooth. The amount of toothpaste used should be limited to the recommended volumes to avoid the development of enamel fluorosis. The professionally performed application of highly concentrated fluoride varnishes, in addition to having a high caries-i...Continue Reading

References

Feb 1, 1990·Journal of Dental Research·B Ogaard
Dec 1, 1988·Acta Odontologica Scandinavica·G Rølla
Apr 17, 1998·Caries Research·J M ten CateM J Buijs
Mar 23, 1999·Community Dentistry and Oral Epidemiology·J D Featherstone
Oct 23, 2001·The Journal of the American Dental Association·J T Autio-Gold, F Courts
Jan 22, 2003·The Cochrane Database of Systematic Reviews·V C MarinhoS Logan
Feb 28, 2004·Community Dentistry and Oral Epidemiology·Wen Sheng RongJia De Wang
Jan 26, 2006·Journal of Dental Research·J A WeintraubS A Gansky
Apr 25, 2007·Journal of Dental Research·S O GriffinV Huntley
Oct 6, 2007·Medical Principles and Practice : International Journal of the Kuwait University, Health Science Centre·Jumana B AmmariPaul F Ashley
Oct 13, 2009·Evidence-based Dentistry·Nicola Innes, Dafydd Evans
Jan 22, 2010·The Cochrane Database of Systematic Reviews·Tanya WalshXin Shi
Jan 21, 2011·Journal of Dental Research·M C M WongH V Worthington
Aug 18, 2012·Advances in Dental Research·A W G Walls, J H Meurman
Apr 6, 2013·Langmuir : the ACS Journal of Surfaces and Colloids·Peter LoskillKarin Jacobs
Jul 13, 2013·The Cochrane Database of Systematic Reviews·Valeria C C MarinhoJan E Clarkson
Nov 8, 2013·Journal of Dental Research·M T KatoM A R Buzalaf
Nov 16, 2014·Journal of Dental Research·R J Wierichs, H Meyer-Lueckel
Jun 16, 2015·The Cochrane Database of Systematic Reviews·Valeria C C MarinhoLee Yee Chong
Nov 3, 2015·Current Oral Health Reports·M D Lagerweij, C van Loveren
Jul 30, 2016·The Cochrane Database of Systematic Reviews·Valeria C C MarinhoTanya Walsh
Feb 2, 2017·Caries Research·Gen MayanagiNobuhiro Takahashi
Aug 8, 2018·Caries Research·Andreas G Schulte, Georgios Tsakos
Sep 5, 2018·European Journal of Oral Sciences·Svante Twetman
Oct 6, 2018·Journal of Dental Research·O UrquhartA Carrasco-Labra
Mar 5, 2019·The Cochrane Database of Systematic Reviews·Tanya WalshAna Jeroncic
Jun 21, 2019·Journal of Dental Research·J M Ten Cate, M A R Buzalaf
Jul 10, 2019·Journal of Dental Research·H P WheltonA J Rugg-Gunn
Oct 22, 2019·European Archives of Paediatric Dentistry : Official Journal of the European Academy of Paediatric Dentistry·K J ToumbaN Α Lygidakis
Dec 8, 2019·Scientific Reports·Kirsch JasminHannig Christian
Dec 12, 2020·Clinical Toxicology : the Official Journal of the American Academy of Clinical Toxicology and European Association of Poisons Centres and Clinical Toxicologists·David D GumminMark L Ryan

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