Use of hematopoietic cell transplants to achieve tolerance in patients with solid organ transplants.

Blood
S Strober

Abstract

The goals of tolerance in patients with solid organ transplants are to eliminate the lifelong need for immunosuppressive (IS) drugs and to prevent graft loss due to rejection or drug toxicity. Tolerance with complete withdrawal of IS drugs has been achieved in recipients of HLA-matched and mismatched living donor kidney transplants in 3 medical centers using hematopoietic cell transplants to establish mixed or complete chimerism.

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Citations

Nov 3, 2016·Current Opinion in Organ Transplantation·Min HuShounan Yi
Jun 3, 2017·Transplantation·Anita Y ChhabraSuzanne Ildstad
Nov 28, 2017·Current Opinion in Organ Transplantation·Ivica Grgic, Anil Chandraker
Jul 26, 2019·American Journal of Hematology·Alina D TanaseStefan O Ciurea
Mar 22, 2019·Transplantation·Franka MessnerGerald Brandacher
Aug 23, 2019·Bone Marrow Transplantation·Shannon R McCurdy, Leo Luznik
Sep 6, 2017·Current Opinion in Organ Transplantation·Katlin B StiversJames B Hoying
May 29, 2019·Plastic and Reconstructive Surgery·Carrie A KubiakPaul S Cederna
Jun 26, 2020·Stem Cells Translational Medicine·Lisa C KadykSohel Talib
Jun 1, 2017·Cell and Tissue Research·Eunsil HahmJochen Reiser
Aug 21, 2020·The Journal of Clinical Investigation·Yuqing LiuDefu Zeng
Nov 25, 2020·Proceedings of the National Academy of Sciences of the United States of America·Shanshan TangDefu Zeng
Mar 30, 2021·Transplantation and Cellular Therapy·Nosha FarhadfarMarcelo Pasquini

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