PMID: 11898734Mar 20, 2002Paper

Use of liver morphometry in the differential diagnosis of chronic alcohol and narcotic poisoning

Sudebno-meditsinskaia ekspertiza
Iu I PigolkinA Kh Amanmuradov

Abstract

Data on the quantitative histomorphological involvement of the liver in chronic narcotic and ethanol poisoning and their combination are presented. Alcohol use by narcomaniacs augments hepatocyte damage, which manifests by increased fatty degeneration, increased activity of lobular hepatitis, appearance of the neutrophil admixture in inflammatory infiltration, and stimulation of sclerotic processes leading to an increase in the perimeter of portal tract section at the expense of connective tissue growth. Quantitative analysis of these processes is recommended for forensic medical histological differential diagnosis of chronic narcotic and ethanol poisoning.

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