Use of local community hospital data for surveillance of antimicrobial resistance

Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America
Susan M Farner

Abstract

We sought to determine whether antimicrobial susceptibility data from a nonteaching community hospital could be used to detect statistically significant local increases in resistance among Streptococcus pneumoniae over a 5-year period. Minimum inhibitory concentrations (MICs) of penicillin and ceftriaxone from 1997-1998 were compared with those from 2000-2001. MICs of penicillin and ceftriaxone for organisms collected in a nonteaching community hospital in central Illinois were used for analysis. The hospital has 224 beds and a catchment area of approximately 40 miles. There were significant increases in MICs of penicillin and ceftriaxone between 1997-1998 and 2000-2001. The MIC of penicillin increased from 0.042 to 0.121 microg/mL (P = .001; 95% confidence interval, -1.713 to -0.388), and the MIC of ceftriaxone increased from 0.028 to 0.071 microg/mL (P = .005; 95% confidence interval, -1.353 to -0.188). There were no significant changes in the percentage of S. pneumoniae isolates that were resistant, intermediate, or susceptible to penicillin and ceftriaxone. MIC data from a community hospital can be used to detect local increases in the rate of resistance before antibiogram data show significant changes. This information is ...Continue Reading

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Citations

Mar 7, 2007·Critical Care Nursing Clinics of North America·Maria A Smith, Leigh Ann McInnis
May 13, 2015·Enfermedades infecciosas y microbiología clínica·Andrés Canut-BlascoLuis Martínez-Martínez
Jul 14, 2011·Emerging Infectious Diseases·James Alesana-SlaterPauline Norris
Nov 5, 2019·Public Health Reports·Allen C BatemanPeter A Shult
Dec 9, 2016·New Zealand Veterinary Journal·L J Toombs-RuaneN P French

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