Use of low-power laser to assist the healing of traumatic wounds in rats

Acta Cirúrgica Brasileira
Fernanda Camila Ferreira da Silva CalistoMárcia Bento Moreira

Abstract

To investigate the morphological aspects of the healing of traumatic wounds in rats using low-power laser. Twenty four non isogenic, young adult male Wistar rats (Rattus norvegicus) weighing between 200 and 300 g was used. The animals were randomly distributed into two groups: Control (GC) and Laser (GL), with 12 animals each. After shaving, anesthesia was performed in the dorsal region and then a surgical procedure using a scalpel was carried out to make the traumatic wound. GL received five sessions of laser therapy in consecutive days using the following laser parameters: wavelength 660 nm, power 100 mW, dose 10 J/cm2. The wounds were evaluated through measurement of the area and depth of the wound (MW) and histological analysis (HA). When comparing the GC with the GL in MW there was a difference in area (p<0.001) and depth (p=0.003) measurement of the wounds in GL. The laser group presented more epithelization than GC (p=0.03). The other histological parameters were similar. The healing of wounds in rats was improved with the use of the laser.

References

Sep 11, 2007·The Journal of Veterinary Medical Science·Akio YasukawaKazuo Takakuda
Oct 27, 2007·Lasers in Surgery and Medicine·Tatiana N Demidova-RiceMichael R Hamblin
Mar 30, 2011·Acta Cirúrgica Brasileira·Valdinaldo Aragão de MeloFábio Ursulino Reis Carvalho
Sep 14, 2011·Photochemistry and Photobiology·Rodrigo Labat MarcosRodrigo Álvaro Brandão Lopes-Martins

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