PMID: 7082523Jun 1, 1982Paper

Use of midazolam as an induction agent: comparison with thiopentone

British Journal of Anaesthesia
S JensenM S Hüttel


A prospective, randomized, single-blind investigation was undertaken into the value of midazolam as an agent for the induction of anaesthesia. Sixty patients undergoing orthopaedic surgery of short duration were allocated randomly to receive either midazolam 0.2 mg kg-1 or thiopentone 3 mg kg-1. The induction time (measured as the time until loss of eyelash reflex) in the thiopentone group was significantly shorter than in the midazolam group. No differences were observed between the two drugs as regards time to onset of apnoea, or changes in heart rate and arterial pressure.


Dec 1, 1983·Anaesthesia·S SjövallO Viinamäki
Sep 1, 1983·Canadian Anaesthetists' Society Journal·R B Forbes
Feb 1, 1995·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·T ElwoodC MacAdams
Jun 30, 2011·Journal of Pharmacy Practice·Thomas R ScarponciniDaniel P Hays
Jan 1, 1990·Acta Anaesthesiologica Scandinavica. Supplementum·P M Lauven, P J Kulka
Jun 1, 1984·Journal of Dental Research·L J Peterson

Related Concepts

Anesthesia, Intravenous
Anesthetic Effect
Diastolic Blood Pressure
Pulse Rate

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