PMID: 6988461Feb 1, 1980Paper

Use of morphometry and immunohistochemistry of small intestinal biopsy specimens in the diagnosis of food allergy

Journal of Clinical Pathology
P C RosekransJ Lindeman

Abstract

Eight babies with cow's milk protein intolerance and malabsorption, ages ranging from 2 weeks to 6 months, and five adult patients with a history of food allergy were studied. In the jejunal biopsies of the eight children with cow's milk protein intolerance we found partial villous atrophy with an increased number of interepithelial lymphocytes as determined by morphometric analysis. In the five adult patients no morphological changes of the jejunal mucosa were found. However, immunoperoxidase staining revealed a markedly increased number of IgE containing cells in the lamina propria of all jejunal biopsies studied. This proved to be specific for young and adult patients with food allergy. It is concluded that immunohistochemistry of jejunal biopsy specimens is of considerable value in the diagnosis of food allergy.

Citations

Nov 1, 1985·European Journal of Pediatrics·P Forget, J W Arends
Jul 1, 1987·Baillière's Clinical Gastroenterology·D Robertson, R Wright
Feb 23, 1984·The New England Journal of Medicine·K AtkinsonA Dodds
Apr 1, 1997·Journal of Pediatric Gastroenterology and Nutrition·J M LópezE De Miguel
Nov 8, 2001·Journal of Pediatric Gastroenterology and Nutrition·L Garcia-Sancho TellezL Garcia-Sancho
Oct 1, 1994·Acta Paediatrica Japonica; Overseas Edition·J Walker-Smith
Nov 1, 1995·Archives of Disease in Childhood·A StaianoS Auricchio
Mar 1, 1992·Annals of the Rheumatic Diseases·M A van de LaarC J Meijer
Dec 1, 1980·Gut·P C RosekransJ Lindeman
Jan 1, 1981·Virchows Archiv. A, Pathological Anatomy and Histology·P C RosekransC J Meijer
Mar 10, 2015·The Journal of Allergy and Clinical Immunology·M Cecilia Berin
Jan 1, 1990·Food Additives and Contaminants·D A Moneret-VautrinG Faure
Jul 1, 1993·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·O Kortekangas-SavolainenR Einarsson
Nov 1, 1988·The British Journal of Dermatology·K KalimoH Kalimo
Apr 1, 1995·Allergy·F AndréS Cavagna
Jul 6, 2019·Advances in Anatomic Pathology·Yinghuan DaiXiuli Liu
Jan 1, 1990·Springer Seminars in Immunopathology·A M Mowat
Jan 1, 1985·Scandinavian Journal of Gastroenterology. Supplement·P Brandtzaeg

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.