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Use of multiepitope polyproteins in serodiagnosis of active tuberculosis

Clinical and Diagnostic Laboratory Immunology

Jul 3, 2002

Raymond HoughtonSteven G Reed

Abstract

Screening of genomic expression libraries from Mycobacterium tuberculosis with sera from tuberculosis (TB) patients or rabbit antiserum to M. tuberculosis led to the identification of novel antigens capable of detecting specific antibodies to M. tuberculosis. Three antigens, Mtb11 (also...read more

Mentioned in this Paper

3-(4-((2,6-dichloropyridin-4-yl)ethynyl)phenyl)propanoic acid
Polyproteins
Procedure to Identify Antibody
Mtb81 protein, Mycobacterium tuberculosis
Lung
Genome
Tuberculosis
Chimeric Proteins, Recombinant
Serodiagnosis
Tuberculosis, Meningeal
54
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Use of multiepitope polyproteins in serodiagnosis of active tuberculosis

Clinical and Diagnostic Laboratory Immunology

Jul 3, 2002

Raymond HoughtonSteven G Reed

PMID: 12093690

DOI: 10.1128/cdli.9.4.883-891.2002

Abstract

Screening of genomic expression libraries from Mycobacterium tuberculosis with sera from tuberculosis (TB) patients or rabbit antiserum to M. tuberculosis led to the identification of novel antigens capable of detecting specific antibodies to M. tuberculosis. Three antigens, Mtb11 (also...read more

Mentioned in this Paper

3-(4-((2,6-dichloropyridin-4-yl)ethynyl)phenyl)propanoic acid
Polyproteins
Procedure to Identify Antibody
Mtb81 protein, Mycobacterium tuberculosis
Lung
Genome
Tuberculosis
Chimeric Proteins, Recombinant
Serodiagnosis
Tuberculosis, Meningeal
54

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