Use of new imaging techniques to predict tumour response to therapy.

The Lancet Oncology
Vanessa N HarryFiona J Gilbert

Abstract

Imaging of tumour response to therapy has steadily evolved over the past few years as a result of advances in existing imaging modalities and the introduction of new functional techniques. The use of imaging as an early surrogate biomarker of response is appealing, because it might allow for a window of opportunity during which treatment regimens can be tailored accordingly, depending on the expected response. The clinical effect of this would ultimately result in a reduction in morbidity and undue costs. The aim of this review is to describe the potential of various new imaging techniques as biomarkers of early tumour response. We have reviewed the literature and identified studies that have assessed these techniques, such as diffusion-weighted MRI, dynamic contrast-enhanced MRI, magnetic resonance spectroscopy, and 18-fluorodeoxyglucose-PET as early response indicators, and highlight the current clinical awareness of their use.

References

Oct 1, 1996·International Journal of Radiation Oncology, Biology, Physics·N A MayrD H Hussey
Feb 25, 1999·Journal of Magnetic Resonance Imaging : JMRI·T SugaharaM Takahashi
Feb 16, 2000·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·H YoungP Price
Dec 6, 2000·Journal of Magnetic Resonance Imaging : JMRI·N A MayrJ M Buatti
Dec 21, 2000·Journal of the National Cancer Institute·T L ChenevertB D Ross
Mar 29, 2001·Journal of Magnetic Resonance Imaging : JMRI·E A BossJ O Barentsz
Mar 15, 2003·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Yael MardorThomas Tichler
Jun 28, 2003·International Journal of Radiation Oncology, Biology, Physics·Alexander F DeVriesWerner Judmaier
Jul 16, 2003·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Wolfgang A WeberMarkus Schwaiger
Nov 25, 2003·Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al]·Christian KremserAlexander de Vries
Dec 16, 2003·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Katja OttWolfgang A Weber
May 14, 2004·Neoplasia : an International Journal for Oncology Research·Yael MardorRaphael Pfeffer
Aug 18, 2004·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Robert J DowneyValerie Rusch
Aug 19, 2004·European Radiology·Scott I K SempleShailesh Chaturvedi
Dec 22, 2004·Archives of Otolaryngology--head & Neck Surgery·David L SchwartzKenneth Krohn
Feb 19, 2005·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Ryohei SasakiJames D Cox
Feb 22, 2005·Neoplasia : an International Journal for Oncology Research·Rebecca J TheilmannAlison Stopeck
Apr 5, 2005·Proceedings of the National Academy of Sciences of the United States of America·Bradford A MoffatBrian D Ross
Apr 20, 2005·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Andrea G RockallRodney H Reznek
Apr 29, 2005·American Journal of Otolaryngology·Noriaki TomuraMasato Sageshima
May 21, 2005·Journal of Magnetic Resonance Imaging : JMRI·Yoshiharu OhnoKazuro Sugimura
Sep 1, 2005·European Journal of Nuclear Medicine and Molecular Imaging·Rodney J HicksLester J Peters
Nov 4, 2005·Proceedings of the National Academy of Sciences of the United States of America·Daniel A HamstraBrian D Ross
Dec 3, 2005·Cancer Imaging : the Official Publication of the International Cancer Imaging Society·Anwar R Padhani
Jan 5, 2006·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Suparna Bonthala WedamSandra M Swain
Jan 7, 2006·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·Christoph PöttgenMartin Stuschke
Mar 29, 2006·Journal of Vascular and Interventional Radiology : JVIR·Ihab R KamelJean-Francois H Geschwind
Jun 22, 2006·Annals of Oncology : Official Journal of the European Society for Medical Oncology·S I K SempleF J Gilbert
Aug 10, 2006·Breast Cancer Research and Treatment·Garry M McDermottSteven D Heys
Aug 19, 2006·Magnetic Resonance Imaging·Martin D PicklesLindsay W Turnbull
Aug 24, 2006·European Journal of Radiology·Takeshi NagashimaMasaru Miyazaki
Nov 8, 2006·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Caroline RousseauMario Campone
Nov 15, 2006·European Journal of Nuclear Medicine and Molecular Imaging·Susanne Martina EschmannRoland Bares

❮ Previous
Next ❯

Citations

May 15, 2013·Pediatric Radiology·Rakhee S GawandeHeike E Daldrup-Link
Feb 1, 2011·Abdominal Imaging·Kyung Won KimByung Ihn Choi
Jun 29, 2013·Abdominal Imaging·Yang GuoFrank H Miller
May 31, 2012·Molecular Imaging and Biology : MIB : the Official Publication of the Academy of Molecular Imaging·Jennifer G WhisenantThomas E Yankeelov
Oct 1, 2010·Cancer Imaging : the Official Publication of the International Cancer Imaging Society·A AfaqD M Koh
Apr 30, 2011·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·Craig J GalbánBrian D Ross
Apr 21, 2012·Breast Cancer Research : BCR·Jonathan K P BegleyFiona J Gilbert
Mar 13, 2014·PloS One·Kirsty I MunroHilary O D Critchley
Jul 8, 2010·Clinical Chemistry and Laboratory Medicine : CCLM·Mario Plebani
Jun 26, 2013·AJR. American Journal of Roentgenology·Atul Bhanudas ShinagareNikhil H Ramaiya
Aug 13, 2010·Biomarkers in Medicine·Yuqiu Jiang, Mu Wang
Feb 3, 2011·World Journal of Radiology·Huaijun WangYicheng Ni
Apr 26, 2014·World Journal of Gastroenterology : WJG·Suk Hee HeoHeoung-Keun Kang
Jul 14, 2010·Targeted Oncology·Astrid A M van der VeldtEpie Boven
May 6, 2014·European Journal of Medicinal Chemistry·Ajay N SinghXiankai Sun
Sep 12, 2014·Science Translational Medicine·Stephen A Boppart, Rebecca Richards-Kortum
Nov 16, 2011·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Roberto García FigueirasPeter L Choyke
Aug 27, 2010·The British Journal of Radiology·D G Hirst, T Robson
Dec 18, 2013·Cancer Imaging : the Official Publication of the International Cancer Imaging Society·Livia BernardinNandita M Desouza
Jan 18, 2016·Advanced Drug Delivery Reviews·Philippe LambinSean Walsh
Jan 21, 2016·Proceedings of the National Academy of Sciences of the United States of America·Anna-Maria RolleStefan Wiehr
Jul 16, 2015·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Kiaran P McGeeMatt A Bernstein
Jun 26, 2012·Advanced Drug Delivery Reviews·Simona Mura, Patrick Couvreur
Jul 20, 2010·European Journal of Radiology·George LoudosDimitris Psimadas
Feb 29, 2016·Current Oncology Reports·Ingfrid S Haldorsen, Helga B Salvesen
Jan 29, 2013·Journal of Magnetic Resonance Imaging : JMRI·Aki KidoKaori Togashi
Feb 16, 2013·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Jennifer MorozStefan A Reinsberg
Apr 2, 2016·Proceedings of the National Academy of Sciences of the United States of America·Ashish KulkarniShiladitya Sengupta
Aug 21, 2014·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·F E LecouvetUNKNOWN EORTC Imaging Group
Jul 20, 2011·Acta Oncologica·Ingerid Skjei KnudtsenEirik Malinen

❮ Previous
Next ❯

Related Concepts

Related Feeds

Apoptosis

Apoptosis is a specific process that leads to programmed cell death through the activation of an evolutionary conserved intracellular pathway leading to pathognomic cellular changes distinct from cellular necrosis

Arterial-Venous in Development & Disease

Arterial-venous development may play a crucial role in cardiovascular diseases. Here is the latest research.

Cancer Metabolism: Therapeutic Targets

Targeting the mechanisms by which cancer cells acquire energy for metabolic needs is a therapeutic target. Discover the latest research on cancer metabolism and therapeutic targets.

Cancer Imaging

Imaging techniques, including CT and MR, have become essential to tumor detection, diagnosis, and monitoring. Here is the latest research on cancer imaging.

Apoptosis in Cancer

Apoptosis is an important mechanism in cancer. By evading apoptosis, tumors can continue to grow without regulation and metastasize systemically. Many therapies are evaluating the use of pro-apoptotic activation to eliminate cancer growth. Here is the latest research on apoptosis in cancer.

Cancer Metabolism

In order for cancer cells to maintain rapid, uncontrolled cell proliferation, they must acquire a source of energy. Cancer cells acquire metabolic energy from their surrounding environment and utilize the host cell nutrients to do so. Here is the latest research on cancer metabolism.

Angiogenesis Inhibitors to Treat Cancer

Cancer treatments including angiogenesis inhibitors prevent tumor cells from receiving nutrients and oxygen. Here is the latest research on angiogenesis inhibitors for the treatment of cancer.